Cellulose acetate propionate coated titanium: characterization and biotechnological application

Surfaces of pure titanium and Ti coated with cellulose acetate propionate (CAP) have been characterized by means of scanning electron microscopy X ray coupled with elemental microanalysis (SEM-EDS), ellipsometry, atomic force microscopy (AFM) and contact angle measurements. Coating Ti surfaces with...

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Bibliographic Details
Published in:Materials research (São Carlos, São Paulo, Brazil) São Paulo, Brazil), 2007-12, Vol.10 (4), p.469-474
Main Authors: Gomes, Guilherme da Silva, Almeida, Arlete Tavares de, Kosaka, Priscila Monteiro, Rogero, Sizue Ota, Cruz, Áurea Silveira, Ikeda, Tamiko Ichikawa, Petri, Denise Freitas Siqueira
Format: Article
Language:English
Subjects:
cell adhesion
cellulose acetate propionate
ENGINEERING, CHEMICAL
lysozyme
MATERIALS SCIENCE, MULTIDISCIPLINARY
METALLURGY & METALLURGICAL ENGINEERING
titanium
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Summary:Surfaces of pure titanium and Ti coated with cellulose acetate propionate (CAP) have been characterized by means of scanning electron microscopy X ray coupled with elemental microanalysis (SEM-EDS), ellipsometry, atomic force microscopy (AFM) and contact angle measurements. Coating Ti surfaces with CAP ultrathin films reduced original surface roughness. Surface energy and wettability of CAP covered Ti surfaces pure Ti surfaces were similar. The adsorption of lysozyme (LYZ), an antibacterial protein, onto Ti and CAP-coated Ti surfaces has been studied by means of ellipsometry and atomic force microscopy (AFM). The adsorption of LYZ was mainly driven by hydrophobic interaction between protein hydrophobic residues and CAP propyl groups. Pure Ti and CAP coated Ti surfaces presented no cytotoxicity effect and proved to be adequate substrates for cell adhesion. The biocompatibility of CAP coated Ti surfaces was attributed to the surface enrichment in glucopyranosyl residues and short alkyl side groups.
ISSN:1516-1439
1980-5373
1516-1439
DOI:10.1590/S1516-14392007000400023