Acute Recurrent Pericarditis as the Inaugural Manifestation of Familial Mediterranean Fever

Familial Mediterranean fever (FMF) is an inherited autosomal recessive disorder commonly found among individuals of Mediterranean or Middle Eastern descent and caused by Mediterranean Fever gene (MEFV) mutations on chromosome 16. It is the most frequent periodic febrile syndrome among the autoinflam...

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Bibliographic Details
Published in:European journal of case reports in internal medicine 2022-09, Vol.9 (9), p.003542-003542
Main Authors: Hassene, Attout, Amichi, Sofia, Bouhamla, Hichem
Format: Article
Language:English
Subjects:
familial mediterranean fever
pericarditis
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Description
Summary:Familial Mediterranean fever (FMF) is an inherited autosomal recessive disorder commonly found among individuals of Mediterranean or Middle Eastern descent and caused by Mediterranean Fever gene (MEFV) mutations on chromosome 16. It is the most frequent periodic febrile syndrome among the autoinflammatory syndromes. Typical febrile attacks include serosal inflammation, but although FMF is characterized by recurrent polyserositis, there is a little documentation of pericardial disease among patients.  We report the case of a patient who presented recurrent pericarditis. Each episode occurred with a high fever and elevation of the C-reactive protein level. Treatment with colchicine was effective. The patient was found to be heterozygous for the V726A mutation. 
ISSN:2284-2594
2284-2594
DOI:10.12890/2022_003542