Effects of pain and depression on the relationship between household solid fuel use and disability among middle-aged and older adults

Household air pollution (HAP) is suggested to increases people's risk of disability, but mediating mechanisms between HAP and disability remains under-investigated. The aim of this study was to investigate the underlying mechanisms between household air pollution and disability in middle-aged a...

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Bibliographic Details
Published in:Scientific reports 2022-12, Vol.12 (1), p.21270-12, Article 21270
Main Authors: Jia, Zhihao, Gao, Yan, Zhao, Liangyu, Han, Suyue
Format: Article
Language:English
Subjects:
631/477/2811
692/1537
704/844/4081
Aged
Air pollution
China - epidemiology
Correlation analysis
Humanities and Social Sciences
Humans
Indoor air pollution
Indoor air quality
Longitudinal Studies
Middle age
Middle Aged
multidisciplinary
Older people
Pain
Prospective Studies
Regression analysis
Retirement
Science
Science (multidisciplinary)
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Summary:Household air pollution (HAP) is suggested to increases people's risk of disability, but mediating mechanisms between HAP and disability remains under-investigated. The aim of this study was to investigate the underlying mechanisms between household air pollution and disability in middle-aged and older adults (i.e., older than 45 years) using a nationally representative prospective cohort. In total, 3754 middle-aged and older adults were selected from the China Health and Retirement Longitudinal Study. Correlation analysis and logistic regression analysis were employed to estimate the association between HAP, pain, depression and disability. Finally, three significant mediation pathways through which HAP directly impacts disability were found: (1) pain (B = 0.09, 95% CI 0.01, 0.02), accounting for 15.25% of the total effect; (2) depression (B = 0.07, 95% CI 0.004, 0.02), accounting for 11.86% of the total effect; (3) pain and depression (B = 0.04, 95% CI 0.003, 0.01), accounting for 6.78% of the total effect. The total mediating effect was 33.89%. This study clarified that HAP can indirectly affect disability through the respective and serial mediating roles of pain and depression. These findings potentially have important implications for national strategies concerning the widespread use of clean fuels by citizens.
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-022-25825-8