Novel Coronavirus disease (COVID-19) in newborns and infants: what we know so far

Recently, an outbreak of viral pneumonitis in Wuhan, Hubei, China successively spread as a global pandemia, led to the identification of a novel betacoronavirus species, the 2019 novel coronavirus, successively designated 2019-nCoV then SARS-CoV-2). The SARS-CoV-2 causes a clinical syndrome designat...

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Bibliographic Details
Published in:Italian journal of pediatrics 2020-04, Vol.46 (1), p.56-56, Article 56
Main Authors: De Rose, Domenico Umberto, Piersigilli, Fiammetta, Ronchetti, Maria Paola, Santisi, Alessandra, Bersani, Iliana, Dotta, Andrea, Danhaive, Olivier, Auriti, Cinzia
Format: Article
Language:English
Subjects:
Betacoronavirus
Breast Feeding
Coronaviridae
Coronavirus
Coronavirus Infections - prevention & control
Coronavirus Infections - therapy
Coronavirus Infections - transmission
Coronaviruses
COVID-19
Epidemiology
Fatalities
Humans
Infant
Infant, Newborn
Infants
Middle East respiratory syndrome
Neonates
Newborns
Pandemics - prevention & control
Pneumonia, Viral - prevention & control
Pneumonia, Viral - therapy
Pneumonia, Viral - transmission
Pneumonitis
Respiratory distress syndrome
Respiratory tract diseases
Review
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
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Summary:Recently, an outbreak of viral pneumonitis in Wuhan, Hubei, China successively spread as a global pandemia, led to the identification of a novel betacoronavirus species, the 2019 novel coronavirus, successively designated 2019-nCoV then SARS-CoV-2). The SARS-CoV-2 causes a clinical syndrome designated coronavirus disease 2019 (COVID19) with a spectrum of manifestations ranging from mild upper respiratory tract infection to severe pneumonitis, acute respiratory distress syndrome (ARDS) and death. Few cases have been observed in children and adolescents who seem to have a more favorable clinical course than other age groups, and even fewer in newborn babies. This review provides an overview of the knowledge on SARS-CoV-2 epidemiology, transmission, the associated clinical presentation and outcomes in newborns and infants up to 6 months of life.
ISSN:1824-7288
1720-8424
1824-7288
DOI:10.1186/s13052-020-0820-x