Vitamin E and Non-Communicable Diseases: A Review

Vitamin E, a nutrient found in several foods, comprises eight lipophilic vitamers, the α-, β-, γ- and δ-tocopherols and the α-, β-, γ- and δ-tocotrienols. This vitamin is capable of exerting antioxidant and anti-inflammatory activities, and acting as immunomodulators. Despite these well-known biolog...

Full description

Saved in:
Bibliographic Details
Published in:Biomedicines 2022-10, Vol.10 (10), p.2473
Main Authors: Ciarcià, Giulia, Bianchi, Simone, Tomasello, Barbara, Acquaviva, Rosaria, Malfa, Giuseppe Antonio, Naletova, Irina, La Mantia, Alfonsina, Di Giacomo, Claudia
Format: Article
Language:English
Subjects:
anti-inflammatory
antioxidant
Antioxidants
Asthma
Bioavailability
Biological activity
Body fat
Breast cancer
Cardiovascular diseases
Cholesterol
Colorectal carcinoma
Cytochrome
diabetes
Diabetes mellitus
Dietary intake
Health aspects
Immunomodulation
Inflammation
Intestinal microflora
Lipid peroxidation
Lipids
Lipophilic
Liver
Lung cancer
Lymphatic system
Metabolism
Metabolites
Oxidation
Prostate cancer
Review
Serum levels
Tocopherols
tocotrienols
Vitamin E
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Vitamin E, a nutrient found in several foods, comprises eight lipophilic vitamers, the α-, β-, γ- and δ-tocopherols and the α-, β-, γ- and δ-tocotrienols. This vitamin is capable of exerting antioxidant and anti-inflammatory activities, and acting as immunomodulators. Despite these well-known biological activities, the findings regarding the ability of vitamin E and its serum metabolites to prevent and/or control chronic disease are often conflicting and inconsistent. In this review, we have described the metabolism of vitamin E and its interaction with the gut microbiota, considering that these factors may be partially responsible for the divergent results obtained. In addition, we focused on the correlations between vitamin E serum levels, dietary intake and/or supplementation, and the main non-communicable diseases, including diabetes mellitus, asthma, cardiovascular diseases, and the four most common cancers (breast cancer, lung cancer, colorectal cancer, and prostate cancer) with the intention of providing an overview of its health effects in the non-communicable-diseases prevention.
ISSN:2227-9059
2227-9059
DOI:10.3390/biomedicines10102473