3078 CT perfusion-guided patient selection and perioperative care in superficial temporal artery-middle cerebral artery bypass surgery: a pilot series

BackgroundSTA-MCA bypass surgery (SMBS) may be considered as a rescue treatment for patients with progressive stroke in the setting of intracranial steno-occlusive cerebrovascular disease despite optimal medical management.The aim of this study was to describe the utility of CT perfusion (CTP) imagi...

Full description

Saved in:
Bibliographic Details
Published in:BMJ neurology open 2024-08, Vol.6 (Suppl 1), p.A28-A28
Main Authors: Goh, Rudy, Bacchi, Stephen, Ovenden, Christopher, Jannes, Jim, Kleinig, Timothy, Abou-Hamden, Amal
Format: Article
Language:English
Subjects:
Heart surgery
Patients
Poster Abstracts
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites
container_end_page A28
container_issue Suppl 1
container_start_page A28
container_title BMJ neurology open
container_volume 6
creator Goh, Rudy
Bacchi, Stephen
Ovenden, Christopher
Jannes, Jim
Kleinig, Timothy
Abou-Hamden, Amal
description BackgroundSTA-MCA bypass surgery (SMBS) may be considered as a rescue treatment for patients with progressive stroke in the setting of intracranial steno-occlusive cerebrovascular disease despite optimal medical management.The aim of this study was to describe the utility of CT perfusion (CTP) imaging in guiding perioperative haemodynamic care for patients receiving SBMS.MethodsThree patients with persistent neurologic deficits pre-SMBS (n=2) and post-SMBS (n=1) underwent CT perfusion on and off pressor support to assess the impact of pressor support on lesion volumes.ResultsIn all three patients (aged 41,43 and 44) CTP imaging demonstrated large Tmax>6s lesions volumes (35, 224 and 380mL respectively). CTP lesion volumes were markedly reduced with pre-operative blood pressure augmentation (13,125 and 289mL respectively). However, radiological improvement was not associated with immediate improvement in clinical outcomes.ConclusionCTP imaging may guide perioperative pressor support care in SMBS. Future studies should determine whether routine use may improve post-operative patient outcomes.
doi_str_mv 10.1136/bmjno-2024-ANZAN.77
format article
fullrecord <record><control><sourceid>proquest_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_6cbf43ea211740a8ac20367da53a6f52</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><doaj_id>oai_doaj_org_article_6cbf43ea211740a8ac20367da53a6f52</doaj_id><sourcerecordid>3099110448</sourcerecordid><originalsourceid>FETCH-LOGICAL-b1348-c63b7a69342886fbb599b9f39ea7b44c34537f83fcfc7f76a109292a98dac8493</originalsourceid><addsrcrecordid>eNpFkctq3DAUhk2h0JDmCboRdO1EN-uS3TD0EgjJJtlkI45kadDgsRzJLsyum75Dn69PUnkmkM3RuXzn14G_ab4QfE0IEzf2sB9TSzHl7ebhZfNwLeWH5oIKRltBOP7UXJWyxxjTDnOl-UXzl2Gp_v3-s31Ck89hKTGN7W6Jve_RBHP044yKH7yb6wDB2K9YTDXU4S-PHGSP4ojKsq5HF2FAsz9MKdcE8uzzsT3Evh8q6rO3721kjxOUUjfzrpa3CNAUh7R-l6Mvn5uPAYbir97ey-b5-7en7c_2_vHH3XZz31rCuGqdYFaC0IxTpUSwttPa6sC0B2k5d4x3TAbFggtOBimAYE01Ba16cIprdtncnXX7BHsz5XiAfDQJojk1Ut6Zem90gzfC2cCZB0qI5BgUOIqZkD10DEToaNX6etaacnpdfJnNPi15rOcbhrUmBHOuKnVzpqpZ7wDBZnXQnBw0q4Pm5KCRkv0HXV2Vgg</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3099110448</pqid></control><display><type>article</type><title>3078 CT perfusion-guided patient selection and perioperative care in superficial temporal artery-middle cerebral artery bypass surgery: a pilot series</title><source>BMJ Open Access Journals</source><source>PubMed (Medline)</source><creator>Goh, Rudy ; Bacchi, Stephen ; Ovenden, Christopher ; Jannes, Jim ; Kleinig, Timothy ; Abou-Hamden, Amal</creator><creatorcontrib>Goh, Rudy ; Bacchi, Stephen ; Ovenden, Christopher ; Jannes, Jim ; Kleinig, Timothy ; Abou-Hamden, Amal</creatorcontrib><description>BackgroundSTA-MCA bypass surgery (SMBS) may be considered as a rescue treatment for patients with progressive stroke in the setting of intracranial steno-occlusive cerebrovascular disease despite optimal medical management.The aim of this study was to describe the utility of CT perfusion (CTP) imaging in guiding perioperative haemodynamic care for patients receiving SBMS.MethodsThree patients with persistent neurologic deficits pre-SMBS (n=2) and post-SMBS (n=1) underwent CT perfusion on and off pressor support to assess the impact of pressor support on lesion volumes.ResultsIn all three patients (aged 41,43 and 44) CTP imaging demonstrated large Tmax&gt;6s lesions volumes (35, 224 and 380mL respectively). CTP lesion volumes were markedly reduced with pre-operative blood pressure augmentation (13,125 and 289mL respectively). However, radiological improvement was not associated with immediate improvement in clinical outcomes.ConclusionCTP imaging may guide perioperative pressor support care in SMBS. Future studies should determine whether routine use may improve post-operative patient outcomes.</description><identifier>EISSN: 2632-6140</identifier><identifier>DOI: 10.1136/bmjno-2024-ANZAN.77</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd</publisher><subject>Heart surgery ; Patients ; Poster Abstracts</subject><ispartof>BMJ neurology open, 2024-08, Vol.6 (Suppl 1), p.A28-A28</ispartof><rights>Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.</rights><rights>2024 Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/ This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ . Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://neurologyopen.bmj.com/content/6/Suppl_1/A28.3.full.pdf$$EPDF$$P50$$Gbmj$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://neurologyopen.bmj.com/content/6/Suppl_1/A28.3.full$$EHTML$$P50$$Gbmj$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,27903,27904,55328,77406,77432</link.rule.ids></links><search><creatorcontrib>Goh, Rudy</creatorcontrib><creatorcontrib>Bacchi, Stephen</creatorcontrib><creatorcontrib>Ovenden, Christopher</creatorcontrib><creatorcontrib>Jannes, Jim</creatorcontrib><creatorcontrib>Kleinig, Timothy</creatorcontrib><creatorcontrib>Abou-Hamden, Amal</creatorcontrib><title>3078 CT perfusion-guided patient selection and perioperative care in superficial temporal artery-middle cerebral artery bypass surgery: a pilot series</title><title>BMJ neurology open</title><addtitle>BMJ Neurol Open</addtitle><description>BackgroundSTA-MCA bypass surgery (SMBS) may be considered as a rescue treatment for patients with progressive stroke in the setting of intracranial steno-occlusive cerebrovascular disease despite optimal medical management.The aim of this study was to describe the utility of CT perfusion (CTP) imaging in guiding perioperative haemodynamic care for patients receiving SBMS.MethodsThree patients with persistent neurologic deficits pre-SMBS (n=2) and post-SMBS (n=1) underwent CT perfusion on and off pressor support to assess the impact of pressor support on lesion volumes.ResultsIn all three patients (aged 41,43 and 44) CTP imaging demonstrated large Tmax&gt;6s lesions volumes (35, 224 and 380mL respectively). CTP lesion volumes were markedly reduced with pre-operative blood pressure augmentation (13,125 and 289mL respectively). However, radiological improvement was not associated with immediate improvement in clinical outcomes.ConclusionCTP imaging may guide perioperative pressor support care in SMBS. Future studies should determine whether routine use may improve post-operative patient outcomes.</description><subject>Heart surgery</subject><subject>Patients</subject><subject>Poster Abstracts</subject><issn>2632-6140</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>9YT</sourceid><sourceid>DOA</sourceid><recordid>eNpFkctq3DAUhk2h0JDmCboRdO1EN-uS3TD0EgjJJtlkI45kadDgsRzJLsyum75Dn69PUnkmkM3RuXzn14G_ab4QfE0IEzf2sB9TSzHl7ebhZfNwLeWH5oIKRltBOP7UXJWyxxjTDnOl-UXzl2Gp_v3-s31Ck89hKTGN7W6Jve_RBHP044yKH7yb6wDB2K9YTDXU4S-PHGSP4ojKsq5HF2FAsz9MKdcE8uzzsT3Evh8q6rO3721kjxOUUjfzrpa3CNAUh7R-l6Mvn5uPAYbir97ey-b5-7en7c_2_vHH3XZz31rCuGqdYFaC0IxTpUSwttPa6sC0B2k5d4x3TAbFggtOBimAYE01Ba16cIprdtncnXX7BHsz5XiAfDQJojk1Ut6Zem90gzfC2cCZB0qI5BgUOIqZkD10DEToaNX6etaacnpdfJnNPi15rOcbhrUmBHOuKnVzpqpZ7wDBZnXQnBw0q4Pm5KCRkv0HXV2Vgg</recordid><startdate>20240801</startdate><enddate>20240801</enddate><creator>Goh, Rudy</creator><creator>Bacchi, Stephen</creator><creator>Ovenden, Christopher</creator><creator>Jannes, Jim</creator><creator>Kleinig, Timothy</creator><creator>Abou-Hamden, Amal</creator><general>BMJ Publishing Group Ltd</general><general>BMJ Publishing Group LTD</general><general>BMJ Publishing Group</general><scope>9YT</scope><scope>ACMMV</scope><scope>K9.</scope><scope>DOA</scope></search><sort><creationdate>20240801</creationdate><title>3078 CT perfusion-guided patient selection and perioperative care in superficial temporal artery-middle cerebral artery bypass surgery: a pilot series</title><author>Goh, Rudy ; Bacchi, Stephen ; Ovenden, Christopher ; Jannes, Jim ; Kleinig, Timothy ; Abou-Hamden, Amal</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b1348-c63b7a69342886fbb599b9f39ea7b44c34537f83fcfc7f76a109292a98dac8493</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Heart surgery</topic><topic>Patients</topic><topic>Poster Abstracts</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Goh, Rudy</creatorcontrib><creatorcontrib>Bacchi, Stephen</creatorcontrib><creatorcontrib>Ovenden, Christopher</creatorcontrib><creatorcontrib>Jannes, Jim</creatorcontrib><creatorcontrib>Kleinig, Timothy</creatorcontrib><creatorcontrib>Abou-Hamden, Amal</creatorcontrib><collection>BMJ Open Access Journals</collection><collection>BMJ Journals:Open Access</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>BMJ neurology open</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Goh, Rudy</au><au>Bacchi, Stephen</au><au>Ovenden, Christopher</au><au>Jannes, Jim</au><au>Kleinig, Timothy</au><au>Abou-Hamden, Amal</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>3078 CT perfusion-guided patient selection and perioperative care in superficial temporal artery-middle cerebral artery bypass surgery: a pilot series</atitle><jtitle>BMJ neurology open</jtitle><stitle>BMJ Neurol Open</stitle><date>2024-08-01</date><risdate>2024</risdate><volume>6</volume><issue>Suppl 1</issue><spage>A28</spage><epage>A28</epage><pages>A28-A28</pages><eissn>2632-6140</eissn><abstract>BackgroundSTA-MCA bypass surgery (SMBS) may be considered as a rescue treatment for patients with progressive stroke in the setting of intracranial steno-occlusive cerebrovascular disease despite optimal medical management.The aim of this study was to describe the utility of CT perfusion (CTP) imaging in guiding perioperative haemodynamic care for patients receiving SBMS.MethodsThree patients with persistent neurologic deficits pre-SMBS (n=2) and post-SMBS (n=1) underwent CT perfusion on and off pressor support to assess the impact of pressor support on lesion volumes.ResultsIn all three patients (aged 41,43 and 44) CTP imaging demonstrated large Tmax&gt;6s lesions volumes (35, 224 and 380mL respectively). CTP lesion volumes were markedly reduced with pre-operative blood pressure augmentation (13,125 and 289mL respectively). However, radiological improvement was not associated with immediate improvement in clinical outcomes.ConclusionCTP imaging may guide perioperative pressor support care in SMBS. Future studies should determine whether routine use may improve post-operative patient outcomes.</abstract><cop>London</cop><pub>BMJ Publishing Group Ltd</pub><doi>10.1136/bmjno-2024-ANZAN.77</doi><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier EISSN: 2632-6140
ispartof BMJ neurology open, 2024-08, Vol.6 (Suppl 1), p.A28-A28
issn 2632-6140
language eng
recordid cdi_doaj_primary_oai_doaj_org_article_6cbf43ea211740a8ac20367da53a6f52
source BMJ Open Access Journals; PubMed (Medline)
subjects Heart surgery
Patients
Poster Abstracts
title 3078 CT perfusion-guided patient selection and perioperative care in superficial temporal artery-middle cerebral artery bypass surgery: a pilot series
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-27T22%3A11%3A56IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=3078%E2%80%85CT%20perfusion-guided%20patient%20selection%20and%20perioperative%20care%20in%20superficial%20temporal%20artery-middle%20cerebral%20artery%20bypass%20surgery:%20a%20pilot%20series&rft.jtitle=BMJ%20neurology%20open&rft.au=Goh,%20Rudy&rft.date=2024-08-01&rft.volume=6&rft.issue=Suppl%201&rft.spage=A28&rft.epage=A28&rft.pages=A28-A28&rft.eissn=2632-6140&rft_id=info:doi/10.1136/bmjno-2024-ANZAN.77&rft_dat=%3Cproquest_doaj_%3E3099110448%3C/proquest_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-b1348-c63b7a69342886fbb599b9f39ea7b44c34537f83fcfc7f76a109292a98dac8493%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=3099110448&rft_id=info:pmid/&rfr_iscdi=true