Diagnostic accuracy of SPECT/CT arthrography in patients with suspected aseptic joint prostheses loosening

Purpose To evaluate the diagnostic accuracy of SPECT/CT arthrography in patients with suspected aseptic prosthesis loosening following hip and knee arthroplasty. Methods A retrospective review of 63 SPECT/CT arthrogram studies (36 knees and 27 hips) between February 1, 2013, and July 1, 2018, was co...

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Bibliographic Details
Published in:European journal of hybrid imaging 2021-02, Vol.5 (1), p.4-4, Article 4
Main Authors: Bao, Bo, Liu, Crystal S., Masson, Edward C. O., Abele, Jonathan T.
Format: Article
Language:English
Subjects:
Accuracy
Arthroplasty (hip)
Arthroplasty (knee)
Bone implants
Diagnostic systems
Evaluation
Hip
Imaging
Joint replacement surgery
Joint surgery
Knee
Loosening
Medical diagnosis
Medicine
Medicine & Public Health
Nuclear Medicine
Original
Original Article
Pain
Prostheses
Prosthetics
Radiology
Single photon emission computed tomography
SPECT/CT
Total hip arthroplasty
Total knee arthroplasty
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Summary:Purpose To evaluate the diagnostic accuracy of SPECT/CT arthrography in patients with suspected aseptic prosthesis loosening following hip and knee arthroplasty. Methods A retrospective review of 63 SPECT/CT arthrogram studies (36 knees and 27 hips) between February 1, 2013, and July 1, 2018, was conducted. All patients underwent clinical and radiologic evaluation as part of their assessment for persistent pain following hip and knee arthroplasty. The detection of tracer activity along the bone-prosthetic interface on SPECT/CT suggests aseptic loosening. Operative assessment as well as clinical/radiologic follow-up at a minimum of 1 year was used as the reference standard. Results The sensitivity and specificity of SPECT/CT for detection of aseptic loosening was 6/7 (86%) and 55/56 (98%), respectively. This gives a positive predictive value (PPV) of 6/7 (86%), a negative predictive value (NPV) of 55/56 (98%), and a diagnostic accuracy of 61/63 (97%). Conclusion SPECT/CT arthrography has a high diagnostic accuracy (97%) in the evaluation of loosening of both hip and knee arthroplasties in patients with persistent post-procedural pain.
ISSN:2510-3636
2510-3636
DOI:10.1186/s41824-021-00098-y