The UK INFINITY Study - Early Experience and Complications of a Multicenter series of 504 Total Ankle Arthroplasties

• Published in: Foot & ankle orthopaedics 2020-10, Vol.5 (4)
• Main Authors: Townshend, David N., Kakwani, Rajesh, Aradhyula, Murty N., Mckinley, John C., Shalaby, Hisham, Smith, Robert, Davenport, James H., Karski, Michael, Clough, Timothy, Blundell, Chris, Davies, Howard, Raglan, Martin, Dhar, Sunil, Hepple, Steve, Taylor, Heath, Davis, James, Sharpe, Ian T., Bing, Andrew J., Goldberg, Andrew J.
• Format: Article
• Language: English
• Subjects: Ankle; Arthritis; Patients; Prostheses
• ISSN: 2473-0114; 2473-0114
• DOI: 10.1177/2473011420S00085

Category Ankle Arthritis; Ankle Introduction/Purpose: This is the first report from the UK INFINITY study. This is a multicentre, non-inventor, prospective observational study of 504 INFINITY fixed bearing total ankle arthroplasties. We report our early experience, complications, radiographic and functional outcomes of this prosthesis. Methods: Patients were recruited from 11 specialist centres between June 2016 and November 2019. Demographic, radiographic, and functional outcome data (Ankle Osteoarthritis Scale, Manchester Oxford Questionnaire and Euroquol 5D-5L) were collected preoperatively, at 6 months (454 patients), 1 year (328 patients) and 2 years (104 patients). The average age was 67.8 (range 23.9 to 88.5) and average BMI 29.9 (18.9 to 48.0). The COFAS grading system was used to stratify deformity. There were 259 (51.4%) COFAS Type 1, 122 (24.2%) COFAS Type 2, 32 (6.3%) COFAS 3 and 87 (17.3%) COFAS type 4. 38 patients (7.54%) presented with inflammatory arthritis. 101 (20.0%) of implantations utilised patient specific instrumentation (Prophecy). 169 (33.5%) of patients underwent an additional procedure at the time of surgery. Early and late complications and reoperations were recorded as adverse events. Radiographs were assessed for lucencies, cysts and/or subsidence. Results: There was a significant (p