Preoperative hypoalbuminaemia in liver surgery: an observational study at a university medical centre

ObjectivesPreoperative hypoalbuminaemia is associated with adverse outcome, including increased postoperative mortality in cardiovascular surgery, neurosurgery, trauma and orthopaedic surgery. However, much less is known about the association between preoperative serum albumin and clinical outcomes...

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Bibliographic Details
Published in:BMJ open 2023-05, Vol.13 (5), p.e068405-e068405
Main Authors: Kuhlmann, Anna Dorothea, Spies, Claudia, Schulte, Erika, Jara, Maximilian, von Haefen, Clarissa, Mertens, Mandy, Süß, Laura Anouk, Winkler, Nathalie, Lachmann, Gunnar, Lachmann, Cornelia
Format: Article
Language:English
Subjects:
Academic Medical Centers
Adult intensive & critical care
Alcohol use
Anaesthesia
Anaesthesia in oncology
Ascites
Clinical Trial
Delirium
Hepatectomy
Hepatobiliary disease
Hepatobiliary surgery
Humans
Hypoalbuminemia - epidemiology
Laboratories
Liver
Liver cancer
Liver cirrhosis
Metastasis
Mortality
NUTRITION & DIETETICS
Observational studies
Patients
Postoperative Complications - epidemiology
Postoperative period
Risk Factors
Serum Albumin
Surgery
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Summary:ObjectivesPreoperative hypoalbuminaemia is associated with adverse outcome, including increased postoperative mortality in cardiovascular surgery, neurosurgery, trauma and orthopaedic surgery. However, much less is known about the association between preoperative serum albumin and clinical outcomes after liver surgery. In this study, we sought to determine whether hypoalbuminaemia before partial hepatectomy is associated with a worse postoperative outcome.DesignObservational study.SettingUniversity Medical Centre in Germany.ParticipantsWe analysed 154 patients enrolled in the perioperative PHYsostigmine prophylaxis for liver resection patients at risk for DELIrium and postOperative cognitive dysfunction (PHYDELIO) trial with a preoperative serum albumin assessment. Hypoalbuminaemia was defined as serum albumin
ISSN:2044-6055
2044-6055
DOI:10.1136/bmjopen-2022-068405