The Health-Related Quality of Life, Work Productivity, Healthcare Resource Utilization, and Economic Burden Associated with Levels of Suicidal Ideation Among Patients Self-Reporting Moderately Severe or Severe Major Depressive Disorder in a National Survey

Suicidal ideation (SI) is a cardinal aspect of major depressive disorder (MDD); however, patient-reported outcomes data from large-scale surveys are limited concerning SI in the context of MDD. This study aims to understand the association between varying levels of SI and health-related quality of l...

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Bibliographic Details
Published in:Neuropsychiatric disease and treatment 2021-01, Vol.17, p.111-123
Main Authors: Benson, Carmela, Singer, David, Carpinella, Colleen M, Shawi, May, Alphs, Larry
Format: Article
Language:English
Subjects:
Absenteeism
Adults
Care and treatment
Costs
economic burden
Emergency medical care
Emotional disorders
Employment
Finance
Health aspects
health-related quality of life
major depression
Major depressive disorder
Medical care
Medical care, Cost of
Mental depression
Mood disorders
Original Research
Patients
Productivity
Psychiatric patients
Quality of life
Questionnaires
Resource utilization
Risk factors
Suicidal behavior
Suicidal ideation
Suicides & suicide attempts
Surveys
Utilization
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Summary:Suicidal ideation (SI) is a cardinal aspect of major depressive disorder (MDD); however, patient-reported outcomes data from large-scale surveys are limited concerning SI in the context of MDD. This study aims to understand the association between varying levels of SI and health-related quality of life (HRQoL), work productivity, healthcare resource utilization (HRU), and associated costs in patients with moderately severe/severe MDD. This was a retrospective, cross-sectional analysis of 2013 national survey data. Patients who self-reported moderately severe or severe MDD and completed the Short Form Survey Version 2 (SF-36v2), Work Productivity Loss and Activity Impairment questionnaire (WPAI), and questions related to HRU were analyzed. Direct and indirect costs were calculated. Patients were categorized and analyzed by the level of SI (no SI, low, moderate, and high) based on their response to Item 9 of the Patient Health Questionnaire-9. Among 75,000 respondents, 15.3% self-reported receiving a physician diagnosis of moderately severe or severe MDD and 2.8% of the total sample endorsed some level of SI. Patients with high SI showed a higher burden than patients with no SI, reporting lower mean SF-36v2 mental component summary scores (
ISSN:1176-6328
1178-2021
1178-2021
DOI:10.2147/NDT.S229530