What’s new in musculoskeletal oncology

We reviewed the recent literature related to primary musculoskeletal tumors and metastatic bone tumors. With regard to primary bone tumors, computer navigation systems and three-dimensional-printed prostheses seem to be new treatment options, especially in challenging anatomical locations, such as t...

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Bibliographic Details
Published in:BMC musculoskeletal disorders 2021-08, Vol.22 (1), p.1-704, Article 704
Main Authors: Errani, Costantino, Mavrogenis, Andreas F, Tsukamoto, Shinji
Format: Article
Language:English
Subjects:
Bone cancer
Bone marrow
Bone sarcomas
Bone surgery
Bone tumors
C-reactive protein
Cancer
Care and treatment
Chemotherapy
Curettage
Cysts
Embolization
FDA approval
Fractures
Life span
Long bone
Medical prognosis
Metastases
Metastasis
Metastatic bone tumor
Muscle tissue tumors
Muscular system
Musculoskeletal diseases
Musculoskeletal tumors
Oncology
Oncology, Experimental
Orthopedic surgery
Patients
Pelvis
Prosthetics
Radiation therapy
Review
Sacrum
Sarcoma
Soft tissue sarcomas
Soft tissue tumors
Surgery
Surgical outcomes
Tumors
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Summary:We reviewed the recent literature related to primary musculoskeletal tumors and metastatic bone tumors. With regard to primary bone tumors, computer navigation systems and three-dimensional-printed prostheses seem to be new treatment options, especially in challenging anatomical locations, such as the sacrum and pelvis. Regarding the treatment of giant cell tumor of bone, recent studies have suggested that denosumab administration is related to a higher local recurrence rate following curettage, but a lower local recurrence rate following en bloc resection. In addition, there was no difference in the local recurrence rate at five years after surgery between short-term and long-term denosumab therapy. With regard to soft tissue tumors, percutaneous cryoablation appears to be a new treatment option for extra-abdominal desmoid tumors, with encouraging results. Regarding soft tissue sarcomas, a negative surgical margin of
ISSN:1471-2474
1471-2474
DOI:10.1186/s12891-021-04590-1