Adult attention-deficit/hyperactivity disorder traits in healthy adults associated with brain volumetric data identify precuneus involvement in traffic crashes

This large-scale study including 2548 healthy adults with no clinical attention-deficit/hyperactivity disorder (ADHD) diagnosis intended to clarify the complex relationships between cerebral grey matter volumes (GMVs), ADHD traits, and driving safety behaviours. Path analysis of magnetic resonance i...

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Bibliographic Details
Published in:Scientific reports 2023-12, Vol.13 (1), p.22466-22466, Article 22466
Main Authors: Putra, Handityo Aulia, Park, Kaechang, Oba, Hikaru, Yamashita, Fumio
Format: Article
Language:English
Subjects:
631/378
704/844/1759
Accidents, Traffic
Adult
Attention Deficit Disorder with Hyperactivity - psychology
Attention deficit hyperactivity disorder
Brain - diagnostic imaging
Brain - pathology
Brain research
Cognitive ability
Cortex (parietal)
Gray Matter - diagnostic imaging
Gray Matter - pathology
Humanities and Social Sciences
Humans
Hyperactivity
Magnetic resonance imaging
Magnetic Resonance Imaging - methods
Medical research
multidisciplinary
Neuroimaging
Parietal Lobe - diagnostic imaging
Parietal Lobe - pathology
Questionnaires
Science
Science (multidisciplinary)
Social behavior
Substantia grisea
Citations: Items that this one cites
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Summary:This large-scale study including 2548 healthy adults with no clinical attention-deficit/hyperactivity disorder (ADHD) diagnosis intended to clarify the complex relationships between cerebral grey matter volumes (GMVs), ADHD traits, and driving safety behaviours. Path analysis of magnetic resonance imaging (MRI) results and questionnaires about ADHD traits and traffic crashes over the past decade revealed significant correlations of ADHD traits with different brain regions relevant to different cognitive functions. The left precuneus responsible for visuospatial cognition was the sole region correlated with all ADHD trait categories, suggesting it plays an important role in understanding driving safety and traffic crashes. For the first time, a strong relationship was found among regional GMVs, ADHD traits, and real-life traffic crashes. These insights into the complex interplay may inform the development of an effective intervention with MRI examination to prevent traffic crashes. Large-scale brain volumetric data may further open social applications of behaviour science and neuroimaging.
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-023-49907-3