Successfully Resected Isolated Lateral Lymph Node Recurrence in a Patient with T1 Lower Rectal Cancer: Case Report and Literature Review

• Published in: Journal of the Anus, Rectum and Colon Rectum and Colon, 2024/07/25, Vol.8(3), pp.259-264
• Main Authors: Rifu, Kazuma, Koinuma, Koji, Horie, Hisanaga, Mori, Katsusuke, Naoi, Daishi, Tojo, Mineyuki, Homma, Yuko, Murahashi, Satoshi, Kihara, Atsushi, Mimura, Toshiki, Kitayama, Joji, Sata, Naohiro
• Format: Article
• Language: English
• Subjects: Case Report; case reports; lateral lymph node metastasis; literature review; lymphatic metastasis; rectal neoplasms
• ISSN: 2432-3853; 2432-3853
• DOI: 10.23922/jarc.2024-003

Lateral lymph node (LLN) metastasis in T1 rectal cancer has an incidence of less than 1%. However, its clinical features are largely uncharted. We report a case of LLN metastasis in T1 rectal cancer and review the relevant literature. A 56-year-old female underwent rectal resection for lower rectal cancer 2 years previously (pT1bN0M0). During follow-up, an elevated tumor marker CA19-9 was documented. Enhanced CT and MRI showed a round shape nodule 2 cm in size on the left side of pelvic wall. PET-CT showed high accumulation of FDG in the same lesion, leading to a diagnosis of isolated LLN recurrence. Because no other site of recurrence was detected, surgical resection of the LLN was performed. Microscopic findings were consistent with metastatic lymph node originating from the recent rectal cancer. Adjuvant chemotherapy for six months was given, and patient remains free of recurrent disease seven months after LLN resection. Although LLN recurrence after surgery for T1 rectal cancer is rare, post-surgical follow-up should not be omitted. When LLN metastasis is suspected on CT, MRI and/or PET-CT will be recommended. Surgical resection of LLN metastasis in patients with T1 rectal cancer may lead to favorable outcomes, when recurrence in other areas is not observed.