Immediate Breast Reconstruction Outcomes in Patients with Prior Mantle and Whole Breast Irradiation

Limited studies have detailed the risk of mastectomy with immediate breast reconstruction among women who previously received mantle field radiation. A single institution retrospective review from 2010 to 2020 of patients previously treated with mantle field radiation (MF-RT) and subsequent mastecto...

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Bibliographic Details
Published in:Plastic and reconstructive surgery. Global open 2024-09, Vol.12 (9), p.e6121
Main Authors: Mullen, Barbara L, Mazroua, Muhammad S, Murphy, Brenna M, Boonipat, Thanapoom, Gao, Robert W, Mrdutt, Mary M, Shumway, Dean A, Degnim, Amy C, Vijayasekaran, Aparna
Format: Article
Language:English
Subjects:
Breast
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Summary:Limited studies have detailed the risk of mastectomy with immediate breast reconstruction among women who previously received mantle field radiation. A single institution retrospective review from 2010 to 2020 of patients previously treated with mantle field radiation (MF-RT) and subsequent mastectomy with immediate breast reconstruction was performed. Patients with prior whole breast irradiation (WBI) were also included as a reference group. Demographic, comorbidity, and surgical factors were collected. The primary outcome was major complications, defined as those requiring reoperation, intravenous antibiotics, or debridement. Fourteen patients with prior MF-RT (27 breasts) and 129 with prior WBI (132 breasts) underwent mastectomy with immediate reconstruction. Prior MF-RT patients were significantly younger (43.8 versus 57.5,  
ISSN:2169-7574
2169-7574
DOI:10.1097/GOX.0000000000006121