Association between triglyceride glucose index and subclinical left ventricular systolic dysfunction in patients with type 2 diabetes

• Published in: Lipids in health and disease 2023-03, Vol.22 (1), p.35-35, Article 35
• Main Authors: Chen, Yanyan, Fu, Jianfang, Wang, Yi, Zhang, Ying, Shi, Min, Wang, Cheng, Li, Mengying, Wang, Li, Liu, Xiangyang, Ta, Shengjun, Liu, Liwen, Li, Zeping, Li, Xiaomiao, Zhou, Jie
• Format: Article
• Language: English
• Subjects: Age; Biomarkers; Blood Glucose; Blood pressure; Body mass index; Cardiac arrhythmia; Cardiomyopathy; Cardiovascular disease; Cholesterol; Complications and side effects; Correlation analysis; Diabetes; Diabetes mellitus (non-insulin dependent); Diabetes Mellitus, Type 2; Diagnosis; Fasting; Flow velocity; Gender; Global longitudinal strain; Glucose; Health aspects; Heart; Heart failure; Heart rate; Humans; Hypertension; Insulin; Insulin resistance; Laboratory testing; Left ventricular function; Left ventricular systolic function; Measurement; Normal distribution; Regression analysis; Risk Factors; Triglyceride glucose index; Triglycerides; Type 2 diabetes; Type 2 diabetes mellitus; Ventricle; Ventricular Dysfunction, Left - diagnostic imaging
• ISSN: 1476-511X; 1476-511X
• DOI: 10.1186/s12944-023-01796-1

The triglyceride glucose (TyG) index has been considered a new biomarker for the diagnosis of angiocardiopathy and insulin resistance. However, the association of the TyG index with subclinical left ventricular (LV) systolic dysfunction still lacks comprehensive exploration. This study was carried out to examine this relationship in patients with type 2 diabetes mellitus (T2DM). A total of 150 T2DM patients with preserved LV ejection fraction (LVEF ≥ 50%) from June 2021 to December 2021 were included in this study. The subclinical LV function was evaluated through global longitudinal strain (GLS), with the predefined GLS