Severe gastrointestinal involvement in pediatric IgA vasculitis: a retrospective single-center cohort study in China

ObjectivesThe study aimed to describe the characteristics of gastrointestinal (GI) involvement in a cohort of hospitalized children with IgA vasculitis (IgAV) in China. MethodWe reviewed the records of hospitalized IgAV patients from January 2014 to December 2020 at one tertiary medical center. The...

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Bibliographic Details
Published in:Frontiers in pediatrics 2023-08, Vol.11, p.1194214-1194214
Main Authors: Li, Yifan, Zhang, Xiaomei, Liu, Haimei, Li, Guomin, Guan, Wanzhen, Zhang, Tao, Zeng, Qiaoqian, Gong, Yinv, Xu, Hong, Sun, Li
Format: Article
Language:English
Subjects:
gastrointestinal involvement
IgA vasculitis
pediatric
Pediatrics
severe
treatment
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Summary:ObjectivesThe study aimed to describe the characteristics of gastrointestinal (GI) involvement in a cohort of hospitalized children with IgA vasculitis (IgAV) in China. MethodWe reviewed the records of hospitalized IgAV patients from January 2014 to December 2020 at one tertiary medical center. The patients were divided into the severe GI group and the non-severe GI group according to the presence of massive GI bleeding and complications. The clinical manifestations, laboratory factors, and treatment were analyzed between the two groups. ResultsA total of 1,179 patients were hospitalized due to IgAV. GI involvement was noted in 50% (589) of the patients, of whom 288 (48.9%) had severe GI involvement. GI complications were observed in 34 patients with IgAV with GI involvement. Rare onset age (
ISSN:2296-2360
2296-2360
DOI:10.3389/fped.2023.1194214