Standardized Plant Extract Alleviates the Negative Effects of FMD Vaccination on Animal Performance

• Published in: Animals (Basel) 2020-03, Vol.10 (3), p.455
• Main Authors: Upadhaya, Santi Devi, Kim, Yong Min, Shi, Huan, Le Cour Grandmaison, Josselin, Blanchard, Alexandra, Kim, In Ho
• Format: Article
• Language: English
• Subjects: Body weight; Cattle; Complications and side effects; Diet; Digestibility; Dry matter; Experiments; Feces; Feeds; fmd; Foot & mouth disease; Foot and mouth disease; Haptoglobin; Health aspects; Hogs; immune; Immune status; Livestock; Nitrogen; plant extract; Plant extracts; Prevention; Swine; Vaccination; Vaccines; Veterinary vaccines
• ISSN: 2076-2615; 2076-2615
• DOI: 10.3390/ani10030455

The present study was conducted to assess the efficacy of a plant extract (PE) on growth performance and immune status in foot and mouth disease (FMD)-vaccinated growing pigs. A total of 120 crossed ((Landrace × Yorkshire) × Duroc) growing pigs with an average initial body weight (BW) of 24.66 ± 2.34 kg and an average age of 70 days were randomized into three groups (10 pens; 4 pigs per pen per treatment) as follows: a nonvaccinated negative control group (NV), a FMD vaccinated group (OV), and a third group received a 0.0125% PE supplement after vaccination (PV), in a 6-week trial. The PV group receiving PE supplementation increased ( < 0.05) the BW compared with the OV group, and average daily gain (ADG) during days 1-14, overall and gain-to-feed ratio (G: F) in days 1-14, and dry matter (DM) digestibility at week 6 were higher ( < 0.05) in the PV compared with the OV group. A significant increase ( < 0.05) in haptoglobin concentration was observed in the OV group compared with the NV group at 25 days postvaccination. The inhibition percentage of antibodies against FMD in the sera reached above 50% in the PV group 5 days earlier than in the OV group. The findings suggest that the inclusion of PE in the diet promoted the performance of vaccinated growing pigs.