Anthocyanin supplementation inhibits secretion of pro-inflammatory cytokines in overweight and obese individuals

[Display omitted] •Anthocyanin’s anti-inflammatory properties were investigated.•ACN supplementation significantly decreases blood plasma levels of CCL2.•ACN supplementation significantly decreases blood plasma levels of IL-6.•ACN displays potential as a complementary anti-inflammatory therapeutic a...

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Bibliographic Details
Published in:Journal of functional foods 2020-01, Vol.64, p.103596, Article 103596
Main Authors: Vugic, Lada, Colson, Natalie, Nikbakht, Elham, Gaiz, Almottesembellah, Holland, Olivia J., Kundur, Avinash Reddy, Singh, Indu
Format: Article
Language:English
Subjects:
Anthocyanins
CCL2
Chronic inflammation
IL-6
Obesity
TNF-α
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Summary:[Display omitted] •Anthocyanin’s anti-inflammatory properties were investigated.•ACN supplementation significantly decreases blood plasma levels of CCL2.•ACN supplementation significantly decreases blood plasma levels of IL-6.•ACN displays potential as a complementary anti-inflammatory therapeutic agent. Chronic low-grade inflammation in obese and overweight individuals is associated with an increased risk of type II diabetes and cardiovascular disease. The current trial investigated the anti-inflammatory properties of anthocyanin (ACN) supplementation in lean, overweight and obese individuals. Fifteen lean, ten overweight and ten obese participants consumed ACN (320 mg/day) for 28 days along with their usual diet. ACN supplementation significantly decreased blood plasma levels of CCL2 in the lean, overweight and obese groups (p 
ISSN:1756-4646
2214-9414
DOI:10.1016/j.jff.2019.103596