New advances in protein engineering for industrial applications: Key takeaways

Recent advancements in protein/enzyme engineering have enabled the production of a diverse array of high-value compounds in microbial systems with the potential for industrial applications. The goal of this review is to articulate some of the most recent protein engineering advances in bacteria, yea...

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Bibliographic Details
Published in:Open life sciences 2024-06, Vol.19 (1), p.20220856-9
Main Authors: Ndochinwa, Giles Obinna, Wang, Qing-Yan, Okoro, Nkwachukwu Oziamara, Amadi, Oyetugo Chioma, Nwagu, Tochukwu Nwamaka, Nnamchi, Chukwudi Innocent, Moneke, Anene Nwabu, Odiba, Arome Solomon
Format: Article
Language:English
Subjects:
algae
bacteria
escherichia coli
fungi
industrial biotechnology
protein and enzyme engineering
Review
saccharomyces cerevisiae
thermostability
yeast
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Summary:Recent advancements in protein/enzyme engineering have enabled the production of a diverse array of high-value compounds in microbial systems with the potential for industrial applications. The goal of this review is to articulate some of the most recent protein engineering advances in bacteria, yeast, and other microbial systems to produce valuable substances. These high-value substances include α-farnesene, vitamin B12, fumaric acid, linalool, glucaric acid, carminic acid, mycosporine-like amino acids, patchoulol, orcinol glucoside, -lactic acid, keratinase, α-glucanotransferases, β-glucosidase, seleno-methylselenocysteine, fatty acids, high-efficiency β-glucosidase enzymes, cellulase, β-carotene, physcion, and glucoamylase. Additionally, recent advances in enzyme engineering for enhancing thermostability will be discussed. These findings have the potential to revolutionize various industries, including biotechnology, food, pharmaceuticals, and biofuels.
ISSN:2391-5412
2391-5412
DOI:10.1515/biol-2022-0856