Troponin-T as predictor of mortality in patients attending the emergency department with atrial fibrillation

High-sensitive Troponin-T (hsTnT) is often increased in acute illness and may be of prognostic importance in patients with atrial fibrillation (AF). The aim of this study was to analyse the characteristics and data of patients attending the emergency department (ED) with AF to determine whether age-...

Full description

Saved in:
Bibliographic Details
Published in:BMC cardiovascular disorders 2024-12, Vol.24 (1), p.719-8
Main Authors: Celik, Serkan, Eriksson, Linus Bodeström, Hytting, Jakob, Waldemar, Annette, Mallios, Panagiotis, Berggren, Amanda, Oscarsson, Ellen, Digerfeldt, Christofer, Wijkman, Magnus, Hubbert, Laila
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Atrial fibrillation
Atrial Fibrillation - blood
Atrial Fibrillation - diagnosis
Atrial Fibrillation - mortality
Biomarkers - blood
Comorbidity
Emergency department
Emergency service
Emergency Service, Hospital
Female
Hospitals
Humans
Male
Medical research
Medicine, Experimental
Middle Aged
Mortality
Patient outcomes
Predictive Value of Tests
Prognosis
Registries
Retrospective Studies
Risk Assessment
Risk Factors
Sweden
Time Factors
Troponin T - blood
Troponin-T
Type 2 diabetes
Up-Regulation
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:High-sensitive Troponin-T (hsTnT) is often increased in acute illness and may be of prognostic importance in patients with atrial fibrillation (AF). The aim of this study was to analyse the characteristics and data of patients attending the emergency department (ED) with AF to determine whether age-adjusted hsTnT levels can predict mortality. This retrospective, single centre, register-based cohort study included all patients ≥ 18 years attending the emergency department during 2018 and 2020 with a primary diagnosis at the ED of AF and sampled for hsTnT. Symptoms, comorbidities, lab results, and characteristics were registered. Patients were divided into groups based on hsTnT level ( 50 ng/L). 30-day and 1-year mortality. A total of 625 patients were included (median age 72, and 45% female). All-cause mortality was 2% at 30 days and 8% at 1-year. The hazard ratio (HR) for 30-day mortality was 4.17 (95% confidence interval (CI) 0.49-35.79, p = 0.192) for hsTnT 15-50 ng/L and 9.64 (95% CI 0.98-95.30, p = 0.053) for hsTnT > 50 ng/L compared to hsTnT 
ISSN:1471-2261
1471-2261
DOI:10.1186/s12872-024-04388-8