Geriatric nutritional risk index was associated with in-hospital mortality among cardiac intensive care unit patients

• Published in: Frontiers in nutrition (Lausanne) 2023-08, Vol.10, p.1218738-1218738
• Main Authors: Li, Yuefeng, Wang, Zhengdong, Sun, Tienan, Zhang, Biyang, Liang, Xiangwen
• Format: Article
• Language: English
• Subjects: cardiac intensive care unit; geriatric nutritional risk index; in-hospital mortality; MIMIC-IV database; Nutrition; nutritional status
• ISSN: 2296-861X; 2296-861X
• DOI: 10.3389/fnut.2023.1218738

BackgroundIdentifying risk factors associated with cardiac intensive care unit (CICU) patients' prognosis can help clinicians intervene earlier and thus improve their prognosis. The correlation between the geriatric nutrition risk index (GNRI), which reflects nutritional status, and in-hospital mortality among CICU patients has yet to be established. MethodThe present study retrospectively enrolled 4,698 CICU patients. Based on the nutritional status, the participants were categorized into four groups. The primary endpoint was in-hospital mortality. The length of hospital stay and length of CICU stay were the secondary endpoints. To explore the correlation between nutritional status and in-hospital mortality, a logistic regression analysis was conducted. The nonlinear associations of GNRI with in-hospital mortality were evaluated using restricted cubic spline (RCS). Furthermore, subgroup analyses were conducted to evaluate the effect of the GNRI on in-hospital mortality across different subgroups, with calculation of the p for interaction. ResultA higher risk of malnutrition was significantly linked to an increased incidence of in-hospital mortality (High risk vs. No risk: 26.2% vs. 4.6%, p