A retrospective study of cumulative absolute reduction in axial length after photobiomodulation therapy

• Published in: BMC ophthalmology 2024-04, Vol.24 (1), p.191-191, Article 191
• Main Authors: Qiu, Kaikai, David, Coveney, Li, Ying, Lei, Zhou, Tong, Liyang, Lin, Wen
• Format: Article
• Language: English
• Subjects: Adolescent; Age composition; Age groups; Axial length; Axial Length, Eye; Biometrics; Care and treatment; Child; Child, Preschool; Children; Female; Follow-Up Studies; Humans; Low-Level Light Therapy - methods; Male; Medical equipment; Myopia; Myopia - physiopathology; Myopia - radiotherapy; Photobiomodulation therapy; Refraction, Ocular - physiology; Retrospective; Retrospective Studies; Vision disorders in children
• ISSN: 1471-2415; 1471-2415
• DOI: 10.1186/s12886-024-03427-4

To assess the age and timeline distribution of ocular axial length shortening among myopic children treated with photobiomodulation therapy in the real world situations. Retrospective study of photobiomodulation therapy in Chinese children aged 4 to 13 years old where axial length measurements were recorded and assessed to determine effectiveness at two age groups (4 ∼ 8 years old group and 9 ∼ 13 years old group). Data was collected from myopic children who received photobiomodulation therapy for 6 ∼ 12 months. Effectiveness of myopia control was defined as any follow-up axial length ≤ baseline axial length, confirming a reduction in axial length. Independent t-test was used to compare the effectiveness of the younger group and the older group with SPSS 22.0. 342 myopic children were included with mean age 8.64 ± 2.20 years and baseline mean axial length of 24.41 ± 1.17 mm. There were 85.40%, 46.30%, 71.20% and 58.30% children with axial length shortening recorded at follow-up for 1 month, 3 months, 6 months and 12 months, respectively. With respect to the axial length shortened eyes, the mean axial length difference (standard deviation) was - 0.039 (0.11) mm, -0.032 (0.11) mm, -0.037 (0.12) mm, -0.028 (0.57) mm at 1, 3, 6, and 12-month follow-up, respectively. Greater AL shortening was observed among the older group who had longer baseline axial lengths than the younger group (P