Impact of the coverage of risk-reducing salpingo-oophorectomy by the national insurance system for women with BRCA pathogenic variants in Japan

To determine the impact of the coverage of risk-reducing salpingo-oophorectomy (RRSO) and mastectomy (RRM) as well as genetic testing for BRCA pathogenic variants by the national insurance system in Japan. We compared the clinical background of women who underwent RRSO at our institution before and...

Full description

Saved in:
Bibliographic Details
Published in:Scientific reports 2023-01, Vol.13 (1), p.1018-1018, Article 1018
Main Authors: Nomura, Hidetaka, Abe, Akiko, Fusegi, Atsushi, Yoshimitsu, Teruyuki, Misaka, Satoki, Murakami, Atsushi, Matsumoto, Tsuyoshi, Tsumura, Shiho, Kanno, Motoko, Aoki, Yoichi, Netsu, Sachiho, Omi, Makiko, Tanigawa, Terumi, Okamoto, Sanshiro, Omatsu, Kohei, Yunokawa, Mayu, Kanao, Hiroyuki, Habano, Eri, Arakawa, Hiromi, Kaneko, Keika, Ueki, Arisa, Haruyama, Yurie, Inari, Hitoshi, Ueno, Takayuki
Format: Article
Language:English
Subjects:
631/67
692/308
692/4028
BRCA1 Protein - genetics
BRCA2 Protein - genetics
Breast cancer
Breast Neoplasms - genetics
Breast Neoplasms - pathology
Breast Neoplasms - surgery
Female
Genetic Predisposition to Disease
Genetic screening
Humanities and Social Sciences
Humans
Hysterectomy
Insurance coverage
Japan
Mastectomy
multidisciplinary
Mutation
Oophorectomy
Ovarian Neoplasms - genetics
Ovarian Neoplasms - prevention & control
Ovarian Neoplasms - surgery
Ovariectomy
Salpingo-oophorectomy
Science
Science (multidisciplinary)
Statistical analysis
Surgery
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To determine the impact of the coverage of risk-reducing salpingo-oophorectomy (RRSO) and mastectomy (RRM) as well as genetic testing for BRCA pathogenic variants by the national insurance system in Japan. We compared the clinical background of women who underwent RRSO at our institution before and after its coverage by the national insurance system. Those who underwent RRSO between January 2017 and December 2019 and between April 2020 and March 2022 were classified as Period . A and B, respectively. Overall, 134 women underwent RRSO during the study period. In Period A and B, 45 and 89 women underwent RRSO for the study period was 36 and 24 months, respectively. Compared with Period A, the number of women who underwent RRSO per month increased by threefold in Period B ( p  
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-023-28304-w