Loading…

Nerve ultrasound in amyotrophic lateral sclerosis: systematic review and meta-analysis

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting upper and lower motor neurons, causing progressive atrophy of muscles, hypertonia, and paralysis. This study aimed to evaluate the current evidence and effectiveness of ultrasound in investigating nerve cross-sectional area...

Full description

Saved in:
Bibliographic Details
Published in:Neurological research and practice 2024-10, Vol.6 (1), p.47-13, Article 47
Main Authors: Abdelnaby, Ramy, Shabib, Ahmed Samy, El Din Moawad, Mostafa Hossam, Salem, Talal, Wagih Youssef Awad, Merna, Awad, Peter Dawoud, Maallem, Imene, Atwan, Hany, Rabie, Salma Adel, Mohamed, Khaled Ashraf, Abdelmageed, Hossam, Karkour, Ali M, Elsayed, Mohamed, Cartwright, Michael S
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites cdi_FETCH-LOGICAL-c378t-827b9b6930125966be4d2777789349e94c05755fa8b37f056b7e7b3e0f57910b3
container_end_page 13
container_issue 1
container_start_page 47
container_title Neurological research and practice
container_volume 6
creator Abdelnaby, Ramy
Shabib, Ahmed Samy
El Din Moawad, Mostafa Hossam
Salem, Talal
Wagih Youssef Awad, Merna
Awad, Peter Dawoud
Maallem, Imene
Atwan, Hany
Rabie, Salma Adel
Mohamed, Khaled Ashraf
Abdelmageed, Hossam
Karkour, Ali M
Elsayed, Mohamed
Cartwright, Michael S
description Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting upper and lower motor neurons, causing progressive atrophy of muscles, hypertonia, and paralysis. This study aimed to evaluate the current evidence and effectiveness of ultrasound in investigating nerve cross-sectional area (CSA) of peripheral nerves, vagus and cervical roots in those with ALS compared with healthy controls and to pool the CSA measurements. A systematic search was conducted on Cochrane, Clarivate Web of Science, PubMed, Scopus, and Embase for the mesh terms nerve, ultrasonography, and amyotrophic lateral sclerosis. A quality assessment was performed using the New-Ottawa scale. In addition, a double-arm meta-analysis using Review Manager 5 software version 5.4 was performed. From the seventeen studies included in this review, the overall mean difference showed that individuals with ALS had a significantly smaller CSA in comparison to healthy controls for median, ulnar, C6 root, and phrenic nerves. However, no significant difference in the CSA was found in radial, vagal, sural, and tibial nerves. This study confirmed results of some of the included studies regards the anatomic sites, where nerve atrophy in ALS could be detected to potentially support the diagnosis of ALS. However, we recommend further large, prospective studies to assess the diagnostic value of these anatomical sites for the diagnosis of ALS. Our findings confirmed specific anatomic sites to differentiate ALS patients from healthy controls through ultrasound. However, these findings cannot be used to confirm the ALS diagnosis, but rather assist in differentiating it from other diagnoses. Retrospectively registered on July 30th 2024 in PROSPERO (PROSPERO (york.ac.uk)) with ID574702.
doi_str_mv 10.1186/s42466-024-00346-z
format article
fullrecord <record><control><sourceid>proquest_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_7007aa9889a34bb1883bcf6266cf67a0</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><doaj_id>oai_doaj_org_article_7007aa9889a34bb1883bcf6266cf67a0</doaj_id><sourcerecordid>3117219799</sourcerecordid><originalsourceid>FETCH-LOGICAL-c378t-827b9b6930125966be4d2777789349e94c05755fa8b37f056b7e7b3e0f57910b3</originalsourceid><addsrcrecordid>eNpdUk1v1TAQjBCIVqV_gAOKxIVLwF_x2lwQqvioVMEFuFrrvE2bJyd-2MlDr78etylVy8X2emdG6_FU1UvO3nJu9LushNK6YUI1jEmlm-sn1bFoSymVsU8fnI-q05y3jDEBGoS0z6sjaRVvBcBx9esbpT3VS5gT5rhMm3qYahwPcU5xdzV0dcCZEoY6d4FSzEN-X-dDnmnEuXQT7Qf6U2PhjTRjgxOGQwG9qJ71GDKd3u0n1c_Pn36cfW0uvn85P_t40XQSzNwYAd56bSXjorVae1KbMhaAsVJZsqpjLbRtj8ZL6FmrPRB4SaxvwXLm5Ul1vupuIm7dLg0jpoOLOLjbi5guHaYyaCAHjAGiNcaiVN5zY6Tvei20LisgK1ofVq3d4kfadDQVT8Ij0cedabhyl3HvOFdGqRaKwps7hRR_L5RnNw65oxBworhkJzkHzaEVtkBf_wfdxiUV91aU4BbsDUqsqK5YnxP199Nw5m5i4NYYuBIDdxsDd11Irx6-457y79PlX_MXrdY</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3117219799</pqid></control><display><type>article</type><title>Nerve ultrasound in amyotrophic lateral sclerosis: systematic review and meta-analysis</title><source>Publicly Available Content Database (Proquest) (PQ_SDU_P3)</source><source>PubMed Central Free</source><creator>Abdelnaby, Ramy ; Shabib, Ahmed Samy ; El Din Moawad, Mostafa Hossam ; Salem, Talal ; Wagih Youssef Awad, Merna ; Awad, Peter Dawoud ; Maallem, Imene ; Atwan, Hany ; Rabie, Salma Adel ; Mohamed, Khaled Ashraf ; Abdelmageed, Hossam ; Karkour, Ali M ; Elsayed, Mohamed ; Cartwright, Michael S</creator><creatorcontrib>Abdelnaby, Ramy ; Shabib, Ahmed Samy ; El Din Moawad, Mostafa Hossam ; Salem, Talal ; Wagih Youssef Awad, Merna ; Awad, Peter Dawoud ; Maallem, Imene ; Atwan, Hany ; Rabie, Salma Adel ; Mohamed, Khaled Ashraf ; Abdelmageed, Hossam ; Karkour, Ali M ; Elsayed, Mohamed ; Cartwright, Michael S</creatorcontrib><description>Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting upper and lower motor neurons, causing progressive atrophy of muscles, hypertonia, and paralysis. This study aimed to evaluate the current evidence and effectiveness of ultrasound in investigating nerve cross-sectional area (CSA) of peripheral nerves, vagus and cervical roots in those with ALS compared with healthy controls and to pool the CSA measurements. A systematic search was conducted on Cochrane, Clarivate Web of Science, PubMed, Scopus, and Embase for the mesh terms nerve, ultrasonography, and amyotrophic lateral sclerosis. A quality assessment was performed using the New-Ottawa scale. In addition, a double-arm meta-analysis using Review Manager 5 software version 5.4 was performed. From the seventeen studies included in this review, the overall mean difference showed that individuals with ALS had a significantly smaller CSA in comparison to healthy controls for median, ulnar, C6 root, and phrenic nerves. However, no significant difference in the CSA was found in radial, vagal, sural, and tibial nerves. This study confirmed results of some of the included studies regards the anatomic sites, where nerve atrophy in ALS could be detected to potentially support the diagnosis of ALS. However, we recommend further large, prospective studies to assess the diagnostic value of these anatomical sites for the diagnosis of ALS. Our findings confirmed specific anatomic sites to differentiate ALS patients from healthy controls through ultrasound. However, these findings cannot be used to confirm the ALS diagnosis, but rather assist in differentiating it from other diagnoses. Retrospectively registered on July 30th 2024 in PROSPERO (PROSPERO (york.ac.uk)) with ID574702.</description><identifier>ISSN: 2524-3489</identifier><identifier>EISSN: 2524-3489</identifier><identifier>DOI: 10.1186/s42466-024-00346-z</identifier><identifier>PMID: 39415277</identifier><language>eng</language><publisher>England: Springer Nature B.V</publisher><subject>Amyotrophic lateral sclerosis ; Atrophy ; Diagnosis ; Meta-analysis ; Motor neurons ; Muscles ; Neurodegenerative diseases ; Paralysis ; Peripheral nerves ; Quality control ; Ultrasonic imaging ; Ultrasound ; Vagus nerve</subject><ispartof>Neurological research and practice, 2024-10, Vol.6 (1), p.47-13, Article 47</ispartof><rights>2024. The Author(s).</rights><rights>The Author(s) 2024. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>The Author(s) 2024 2024</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c378t-827b9b6930125966be4d2777789349e94c05755fa8b37f056b7e7b3e0f57910b3</cites><orcidid>0000-0002-1607-1589 ; 0009-0001-3290-0842 ; 0000-0002-4416-9452 ; 0000-0002-7701-1707 ; 0000-0002-6999-7043 ; 0000-0001-5161-2195 ; 0009-0002-9401-7323 ; 0000-0002-0139-2873 ; 0000-0002-5356-3005 ; 0000-0002-4843-2393</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC11484457/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/3117219799?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39415277$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Abdelnaby, Ramy</creatorcontrib><creatorcontrib>Shabib, Ahmed Samy</creatorcontrib><creatorcontrib>El Din Moawad, Mostafa Hossam</creatorcontrib><creatorcontrib>Salem, Talal</creatorcontrib><creatorcontrib>Wagih Youssef Awad, Merna</creatorcontrib><creatorcontrib>Awad, Peter Dawoud</creatorcontrib><creatorcontrib>Maallem, Imene</creatorcontrib><creatorcontrib>Atwan, Hany</creatorcontrib><creatorcontrib>Rabie, Salma Adel</creatorcontrib><creatorcontrib>Mohamed, Khaled Ashraf</creatorcontrib><creatorcontrib>Abdelmageed, Hossam</creatorcontrib><creatorcontrib>Karkour, Ali M</creatorcontrib><creatorcontrib>Elsayed, Mohamed</creatorcontrib><creatorcontrib>Cartwright, Michael S</creatorcontrib><title>Nerve ultrasound in amyotrophic lateral sclerosis: systematic review and meta-analysis</title><title>Neurological research and practice</title><addtitle>Neurol Res Pract</addtitle><description>Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting upper and lower motor neurons, causing progressive atrophy of muscles, hypertonia, and paralysis. This study aimed to evaluate the current evidence and effectiveness of ultrasound in investigating nerve cross-sectional area (CSA) of peripheral nerves, vagus and cervical roots in those with ALS compared with healthy controls and to pool the CSA measurements. A systematic search was conducted on Cochrane, Clarivate Web of Science, PubMed, Scopus, and Embase for the mesh terms nerve, ultrasonography, and amyotrophic lateral sclerosis. A quality assessment was performed using the New-Ottawa scale. In addition, a double-arm meta-analysis using Review Manager 5 software version 5.4 was performed. From the seventeen studies included in this review, the overall mean difference showed that individuals with ALS had a significantly smaller CSA in comparison to healthy controls for median, ulnar, C6 root, and phrenic nerves. However, no significant difference in the CSA was found in radial, vagal, sural, and tibial nerves. This study confirmed results of some of the included studies regards the anatomic sites, where nerve atrophy in ALS could be detected to potentially support the diagnosis of ALS. However, we recommend further large, prospective studies to assess the diagnostic value of these anatomical sites for the diagnosis of ALS. Our findings confirmed specific anatomic sites to differentiate ALS patients from healthy controls through ultrasound. However, these findings cannot be used to confirm the ALS diagnosis, but rather assist in differentiating it from other diagnoses. Retrospectively registered on July 30th 2024 in PROSPERO (PROSPERO (york.ac.uk)) with ID574702.</description><subject>Amyotrophic lateral sclerosis</subject><subject>Atrophy</subject><subject>Diagnosis</subject><subject>Meta-analysis</subject><subject>Motor neurons</subject><subject>Muscles</subject><subject>Neurodegenerative diseases</subject><subject>Paralysis</subject><subject>Peripheral nerves</subject><subject>Quality control</subject><subject>Ultrasonic imaging</subject><subject>Ultrasound</subject><subject>Vagus nerve</subject><issn>2524-3489</issn><issn>2524-3489</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNpdUk1v1TAQjBCIVqV_gAOKxIVLwF_x2lwQqvioVMEFuFrrvE2bJyd-2MlDr78etylVy8X2emdG6_FU1UvO3nJu9LushNK6YUI1jEmlm-sn1bFoSymVsU8fnI-q05y3jDEBGoS0z6sjaRVvBcBx9esbpT3VS5gT5rhMm3qYahwPcU5xdzV0dcCZEoY6d4FSzEN-X-dDnmnEuXQT7Qf6U2PhjTRjgxOGQwG9qJ71GDKd3u0n1c_Pn36cfW0uvn85P_t40XQSzNwYAd56bSXjorVae1KbMhaAsVJZsqpjLbRtj8ZL6FmrPRB4SaxvwXLm5Ul1vupuIm7dLg0jpoOLOLjbi5guHaYyaCAHjAGiNcaiVN5zY6Tvei20LisgK1ofVq3d4kfadDQVT8Ij0cedabhyl3HvOFdGqRaKwps7hRR_L5RnNw65oxBworhkJzkHzaEVtkBf_wfdxiUV91aU4BbsDUqsqK5YnxP199Nw5m5i4NYYuBIDdxsDd11Irx6-457y79PlX_MXrdY</recordid><startdate>20241017</startdate><enddate>20241017</enddate><creator>Abdelnaby, Ramy</creator><creator>Shabib, Ahmed Samy</creator><creator>El Din Moawad, Mostafa Hossam</creator><creator>Salem, Talal</creator><creator>Wagih Youssef Awad, Merna</creator><creator>Awad, Peter Dawoud</creator><creator>Maallem, Imene</creator><creator>Atwan, Hany</creator><creator>Rabie, Salma Adel</creator><creator>Mohamed, Khaled Ashraf</creator><creator>Abdelmageed, Hossam</creator><creator>Karkour, Ali M</creator><creator>Elsayed, Mohamed</creator><creator>Cartwright, Michael S</creator><general>Springer Nature B.V</general><general>BioMed Central</general><general>BMC</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7XB</scope><scope>88G</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>LK8</scope><scope>M2M</scope><scope>M7P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope><orcidid>https://orcid.org/0000-0002-1607-1589</orcidid><orcidid>https://orcid.org/0009-0001-3290-0842</orcidid><orcidid>https://orcid.org/0000-0002-4416-9452</orcidid><orcidid>https://orcid.org/0000-0002-7701-1707</orcidid><orcidid>https://orcid.org/0000-0002-6999-7043</orcidid><orcidid>https://orcid.org/0000-0001-5161-2195</orcidid><orcidid>https://orcid.org/0009-0002-9401-7323</orcidid><orcidid>https://orcid.org/0000-0002-0139-2873</orcidid><orcidid>https://orcid.org/0000-0002-5356-3005</orcidid><orcidid>https://orcid.org/0000-0002-4843-2393</orcidid></search><sort><creationdate>20241017</creationdate><title>Nerve ultrasound in amyotrophic lateral sclerosis: systematic review and meta-analysis</title><author>Abdelnaby, Ramy ; Shabib, Ahmed Samy ; El Din Moawad, Mostafa Hossam ; Salem, Talal ; Wagih Youssef Awad, Merna ; Awad, Peter Dawoud ; Maallem, Imene ; Atwan, Hany ; Rabie, Salma Adel ; Mohamed, Khaled Ashraf ; Abdelmageed, Hossam ; Karkour, Ali M ; Elsayed, Mohamed ; Cartwright, Michael S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c378t-827b9b6930125966be4d2777789349e94c05755fa8b37f056b7e7b3e0f57910b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Amyotrophic lateral sclerosis</topic><topic>Atrophy</topic><topic>Diagnosis</topic><topic>Meta-analysis</topic><topic>Motor neurons</topic><topic>Muscles</topic><topic>Neurodegenerative diseases</topic><topic>Paralysis</topic><topic>Peripheral nerves</topic><topic>Quality control</topic><topic>Ultrasonic imaging</topic><topic>Ultrasound</topic><topic>Vagus nerve</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Abdelnaby, Ramy</creatorcontrib><creatorcontrib>Shabib, Ahmed Samy</creatorcontrib><creatorcontrib>El Din Moawad, Mostafa Hossam</creatorcontrib><creatorcontrib>Salem, Talal</creatorcontrib><creatorcontrib>Wagih Youssef Awad, Merna</creatorcontrib><creatorcontrib>Awad, Peter Dawoud</creatorcontrib><creatorcontrib>Maallem, Imene</creatorcontrib><creatorcontrib>Atwan, Hany</creatorcontrib><creatorcontrib>Rabie, Salma Adel</creatorcontrib><creatorcontrib>Mohamed, Khaled Ashraf</creatorcontrib><creatorcontrib>Abdelmageed, Hossam</creatorcontrib><creatorcontrib>Karkour, Ali M</creatorcontrib><creatorcontrib>Elsayed, Mohamed</creatorcontrib><creatorcontrib>Cartwright, Michael S</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Psychology Database (Alumni)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection (Proquest) (PQ_SDU_P3)</collection><collection>ProQuest Biological Science Collection</collection><collection>ProQuest Psychology Journals</collection><collection>ProQuest Biological Science Journals</collection><collection>Publicly Available Content Database (Proquest) (PQ_SDU_P3)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>Neurological research and practice</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Abdelnaby, Ramy</au><au>Shabib, Ahmed Samy</au><au>El Din Moawad, Mostafa Hossam</au><au>Salem, Talal</au><au>Wagih Youssef Awad, Merna</au><au>Awad, Peter Dawoud</au><au>Maallem, Imene</au><au>Atwan, Hany</au><au>Rabie, Salma Adel</au><au>Mohamed, Khaled Ashraf</au><au>Abdelmageed, Hossam</au><au>Karkour, Ali M</au><au>Elsayed, Mohamed</au><au>Cartwright, Michael S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Nerve ultrasound in amyotrophic lateral sclerosis: systematic review and meta-analysis</atitle><jtitle>Neurological research and practice</jtitle><addtitle>Neurol Res Pract</addtitle><date>2024-10-17</date><risdate>2024</risdate><volume>6</volume><issue>1</issue><spage>47</spage><epage>13</epage><pages>47-13</pages><artnum>47</artnum><issn>2524-3489</issn><eissn>2524-3489</eissn><abstract>Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease affecting upper and lower motor neurons, causing progressive atrophy of muscles, hypertonia, and paralysis. This study aimed to evaluate the current evidence and effectiveness of ultrasound in investigating nerve cross-sectional area (CSA) of peripheral nerves, vagus and cervical roots in those with ALS compared with healthy controls and to pool the CSA measurements. A systematic search was conducted on Cochrane, Clarivate Web of Science, PubMed, Scopus, and Embase for the mesh terms nerve, ultrasonography, and amyotrophic lateral sclerosis. A quality assessment was performed using the New-Ottawa scale. In addition, a double-arm meta-analysis using Review Manager 5 software version 5.4 was performed. From the seventeen studies included in this review, the overall mean difference showed that individuals with ALS had a significantly smaller CSA in comparison to healthy controls for median, ulnar, C6 root, and phrenic nerves. However, no significant difference in the CSA was found in radial, vagal, sural, and tibial nerves. This study confirmed results of some of the included studies regards the anatomic sites, where nerve atrophy in ALS could be detected to potentially support the diagnosis of ALS. However, we recommend further large, prospective studies to assess the diagnostic value of these anatomical sites for the diagnosis of ALS. Our findings confirmed specific anatomic sites to differentiate ALS patients from healthy controls through ultrasound. However, these findings cannot be used to confirm the ALS diagnosis, but rather assist in differentiating it from other diagnoses. Retrospectively registered on July 30th 2024 in PROSPERO (PROSPERO (york.ac.uk)) with ID574702.</abstract><cop>England</cop><pub>Springer Nature B.V</pub><pmid>39415277</pmid><doi>10.1186/s42466-024-00346-z</doi><tpages>13</tpages><orcidid>https://orcid.org/0000-0002-1607-1589</orcidid><orcidid>https://orcid.org/0009-0001-3290-0842</orcidid><orcidid>https://orcid.org/0000-0002-4416-9452</orcidid><orcidid>https://orcid.org/0000-0002-7701-1707</orcidid><orcidid>https://orcid.org/0000-0002-6999-7043</orcidid><orcidid>https://orcid.org/0000-0001-5161-2195</orcidid><orcidid>https://orcid.org/0009-0002-9401-7323</orcidid><orcidid>https://orcid.org/0000-0002-0139-2873</orcidid><orcidid>https://orcid.org/0000-0002-5356-3005</orcidid><orcidid>https://orcid.org/0000-0002-4843-2393</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2524-3489
ispartof Neurological research and practice, 2024-10, Vol.6 (1), p.47-13, Article 47
issn 2524-3489
2524-3489
language eng
recordid cdi_doaj_primary_oai_doaj_org_article_7007aa9889a34bb1883bcf6266cf67a0
source Publicly Available Content Database (Proquest) (PQ_SDU_P3); PubMed Central Free
subjects Amyotrophic lateral sclerosis
Atrophy
Diagnosis
Meta-analysis
Motor neurons
Muscles
Neurodegenerative diseases
Paralysis
Peripheral nerves
Quality control
Ultrasonic imaging
Ultrasound
Vagus nerve
title Nerve ultrasound in amyotrophic lateral sclerosis: systematic review and meta-analysis
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T15%3A13%3A51IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Nerve%20ultrasound%20in%20amyotrophic%20lateral%20sclerosis:%20systematic%20review%20and%20meta-analysis&rft.jtitle=Neurological%20research%20and%20practice&rft.au=Abdelnaby,%20Ramy&rft.date=2024-10-17&rft.volume=6&rft.issue=1&rft.spage=47&rft.epage=13&rft.pages=47-13&rft.artnum=47&rft.issn=2524-3489&rft.eissn=2524-3489&rft_id=info:doi/10.1186/s42466-024-00346-z&rft_dat=%3Cproquest_doaj_%3E3117219799%3C/proquest_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c378t-827b9b6930125966be4d2777789349e94c05755fa8b37f056b7e7b3e0f57910b3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=3117219799&rft_id=info:pmid/39415277&rfr_iscdi=true