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Comparative Study of Biotin and Hydroxyapatite on Biological Properties of Composite Coating

The ultimate goal of using biomaterials is to improve human health by restoring the function of natural living tissues and organs in the body. The present work aims to modify the composite coating layer properties by using two different types of bioactive reinforcing materials (biotin and hydroxyapa...

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Published in:International journal of biomaterials 2022-09, Vol.2022, p.1-11
Main Authors: Hamad, Qahtan A., Al-Hasani, Fatimah J., Faheed, Noor K.
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container_title International journal of biomaterials
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creator Hamad, Qahtan A.
Al-Hasani, Fatimah J.
Faheed, Noor K.
description The ultimate goal of using biomaterials is to improve human health by restoring the function of natural living tissues and organs in the body. The present work aims to modify the composite coating layer properties by using two different types of bioactive reinforcing materials (biotin and hydroxyapatite) particles in different percentages (5% and 10%). Coatings were applied onto commercially pure Ti, SS 316 L, and SS 304 substrates by the dip-coating method. Characterization of samples includes microstructure observation by field emission scanning electron microscopy (FE-SEM), contact angle measurement (wettability), and MTT. The results show the addition of metallic particles (bioparticles) (hydroxyapatite particles, biotin) at 5 Vol. % improved the whole properties of composite materials. Using different particles’ scale size aids to enhance the combinations in the alginate matrix producing a dual effect on composite film properties. In addition, the inclusion of metallic particles has to increase the wettability by reducing the contact angle. At the same time, MTT graphs revealed that after 3 days of exposure in MG-63 cells, 316 L SS alloys’ surface following pack adhesion became more active.
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Hamad et al.</rights><rights>COPYRIGHT 2022 John Wiley &amp; Sons, Inc.</rights><rights>Copyright © 2022 Qahtan A. Hamad et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0</rights><rights>Copyright © 2022 Qahtan A. 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subjects Alginates
Alginic acid
Alloys
Analysis
Biocompatibility
Biological products
Biological properties
Biomaterials
Biomedical materials
Biotin
Coatings
Comparative studies
Composite materials
Contact angle
Corrosion resistance
Degassing of metals
Dip coatings
Emission measurements
Field emission microscopy
Fourier transforms
Hydroxyapatite
Immersion coating
Mechanical properties
Metal particles
Metals
Orthopedics
Particulate composites
Reinforcing materials
Scanning electron microscopy
Stainless steel
Steel alloys
Substrates
Tissues
Titanium
Titanium alloys
Transplants & implants
Wettability
title Comparative Study of Biotin and Hydroxyapatite on Biological Properties of Composite Coating
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