Pulmonary fat embolism: a potentially new fatal complication of SARS-CoV-2 infection. A case report

So far, there have been more than 761 million confirmed cases of SARS-CoV-2 worldwide, with more than 6.8 million deaths. The most common direct causes of death for COVID-19 are diffuse alveolar injury and acute respiratory distress syndrome. Autopsy results have shown that 80-100% of COVID-19 patie...

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Bibliographic Details
Published in:BMC infectious diseases 2023-09, Vol.23 (1), p.1-576, Article 576
Main Authors: Kong, Jiangwei, Yang, Tengfei, Zhang, Fu, Liao, XinBiao, Du, Sihao, Yang, Xingan, Li, Dongri
Format: Article
Language:English
Subjects:
Acute respiratory distress syndrome
Adrenal glands
Alveoli
Anticoagulants
Autopsies
Autopsy
Blood pressure
Blood vessels
C-reactive protein
Case Report
Case reports
COVID-19
Diagnosis
Disease transmission
Embolism
Embolisms
Epidemiology
Epithelial cells
Epithelium
Health aspects
Heart beat
Heart rate
Hemorrhage
Infections
Lungs
Medical screening
Nucleocapsids
Patient outcomes
Patients
Procalcitonin
Proteins
Pulmonary arteries
Pulmonary embolism
Pulmonary embolisms
Pulmonary fat embolism
Pulmonary microthromboembolism
Respiration
Respiratory distress syndrome
Risk factors
SARS-CoV-2
Search and rescue operations
Severe acute respiratory syndrome coronavirus 2
Spike protein
Staining
Thrombosis
Thymus gland
Tungsten compounds
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Summary:So far, there have been more than 761 million confirmed cases of SARS-CoV-2 worldwide, with more than 6.8 million deaths. The most common direct causes of death for COVID-19 are diffuse alveolar injury and acute respiratory distress syndrome. Autopsy results have shown that 80-100% of COVID-19 patients have microthrombi which is 9 times higher than in patients with influenza. There are reported cases of fat embolism associated with Covid-19, but relevant epidemiological investigations and fatal cases of pulmonary fat embolism are lacking. In this report, we describe the first COVID-19 patient to die from pulmonary fat embolism. Pulmonary fat embolism may be another fatal complication of COVID-19 infection, and clinicians should pay more attention to it.
ISSN:1471-2334
1471-2334
DOI:10.1186/s12879-023-08559-4