Loading…
Pulmonary fat embolism: a potentially new fatal complication of SARS-CoV-2 infection. A case report
So far, there have been more than 761 million confirmed cases of SARS-CoV-2 worldwide, with more than 6.8 million deaths. The most common direct causes of death for COVID-19 are diffuse alveolar injury and acute respiratory distress syndrome. Autopsy results have shown that 80-100% of COVID-19 patie...
Saved in:
Published in: | BMC infectious diseases 2023-09, Vol.23 (1), p.1-576, Article 576 |
---|---|
Main Authors: | , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
cited_by | cdi_FETCH-LOGICAL-c609t-890c7a0de8a8d7fbfa1fdead99cf42f8dc5f8f32daf0964cc9c9dabab21ec2893 |
---|---|
cites | cdi_FETCH-LOGICAL-c609t-890c7a0de8a8d7fbfa1fdead99cf42f8dc5f8f32daf0964cc9c9dabab21ec2893 |
container_end_page | 576 |
container_issue | 1 |
container_start_page | 1 |
container_title | BMC infectious diseases |
container_volume | 23 |
creator | Kong, Jiangwei Yang, Tengfei Zhang, Fu Liao, XinBiao Du, Sihao Yang, Xingan Li, Dongri |
description | So far, there have been more than 761 million confirmed cases of SARS-CoV-2 worldwide, with more than 6.8 million deaths. The most common direct causes of death for COVID-19 are diffuse alveolar injury and acute respiratory distress syndrome. Autopsy results have shown that 80-100% of COVID-19 patients have microthrombi which is 9 times higher than in patients with influenza. There are reported cases of fat embolism associated with Covid-19, but relevant epidemiological investigations and fatal cases of pulmonary fat embolism are lacking. In this report, we describe the first COVID-19 patient to die from pulmonary fat embolism. Pulmonary fat embolism may be another fatal complication of COVID-19 infection, and clinicians should pay more attention to it. |
doi_str_mv | 10.1186/s12879-023-08559-4 |
format | article |
fullrecord | <record><control><sourceid>gale_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_7024bdc92b59490da62e9878835b7d83</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A763404432</galeid><doaj_id>oai_doaj_org_article_7024bdc92b59490da62e9878835b7d83</doaj_id><sourcerecordid>A763404432</sourcerecordid><originalsourceid>FETCH-LOGICAL-c609t-890c7a0de8a8d7fbfa1fdead99cf42f8dc5f8f32daf0964cc9c9dabab21ec2893</originalsourceid><addsrcrecordid>eNqNkktv1DAUhSMEoqXwB1hZYkMXGfxKbLNBoxGPkSoVdaBb68aPwVUSD3YC9N_j6VTAIBbIC1v3fj7WPT5V9ZzgBSGyfZUJlULVmLIay6ZRNX9QnRIuSE0Z4w__OJ9UT3K-wZgISdXj6oSJthVEydPKfJz7IY6QbpGHCbmhi33Iw2sEaBcnN04B-v4Wje77vg89MnHY9cHAFOKIokeb5dWmXsXrmqIwemf29QVaIgPZoeR2MU1Pq0ce-uye3e9n1ed3bz-tPtQXl-_Xq-VFbVqsploqbARg6yRIK3zngXjrwCplPKdeWtN46Rm14LFquTHKKAsddJQ4Q6ViZ9X6oGsj3OhdCkMZS0cI-q4Q01ZDmoLpnRaY8s4aRbtGcYUttNQpKaRkTSesZEXrzUFrN3eDs6Y4kaA_Ej3ujOGL3sZvmmBeTBaiKLy8V0jx6-zypIeQjet7GF2cs6ayJQzTRrYFffEXehPnNBav9lTDmvK7-De1hTJBMTuWh81eVC9FyzjmnNFCLf5BlWXdEEwcnQ-lfnTh_OhCYSb3Y9rCnLNeb67-n728PmbpgTUp5pyc_2UewXqfX33Iry751Xf51Zz9BJ893vk</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2865358550</pqid></control><display><type>article</type><title>Pulmonary fat embolism: a potentially new fatal complication of SARS-CoV-2 infection. A case report</title><source>PubMed (Medline)</source><source>Publicly Available Content Database</source><creator>Kong, Jiangwei ; Yang, Tengfei ; Zhang, Fu ; Liao, XinBiao ; Du, Sihao ; Yang, Xingan ; Li, Dongri</creator><creatorcontrib>Kong, Jiangwei ; Yang, Tengfei ; Zhang, Fu ; Liao, XinBiao ; Du, Sihao ; Yang, Xingan ; Li, Dongri</creatorcontrib><description>So far, there have been more than 761 million confirmed cases of SARS-CoV-2 worldwide, with more than 6.8 million deaths. The most common direct causes of death for COVID-19 are diffuse alveolar injury and acute respiratory distress syndrome. Autopsy results have shown that 80-100% of COVID-19 patients have microthrombi which is 9 times higher than in patients with influenza. There are reported cases of fat embolism associated with Covid-19, but relevant epidemiological investigations and fatal cases of pulmonary fat embolism are lacking. In this report, we describe the first COVID-19 patient to die from pulmonary fat embolism. Pulmonary fat embolism may be another fatal complication of COVID-19 infection, and clinicians should pay more attention to it.</description><identifier>ISSN: 1471-2334</identifier><identifier>EISSN: 1471-2334</identifier><identifier>DOI: 10.1186/s12879-023-08559-4</identifier><identifier>PMID: 37667198</identifier><language>eng</language><publisher>London: BioMed Central Ltd</publisher><subject>Acute respiratory distress syndrome ; Adrenal glands ; Alveoli ; Anticoagulants ; Autopsies ; Autopsy ; Blood pressure ; Blood vessels ; C-reactive protein ; Case Report ; Case reports ; COVID-19 ; Diagnosis ; Disease transmission ; Embolism ; Embolisms ; Epidemiology ; Epithelial cells ; Epithelium ; Health aspects ; Heart beat ; Heart rate ; Hemorrhage ; Infections ; Lungs ; Medical screening ; Nucleocapsids ; Patient outcomes ; Patients ; Procalcitonin ; Proteins ; Pulmonary arteries ; Pulmonary embolism ; Pulmonary embolisms ; Pulmonary fat embolism ; Pulmonary microthromboembolism ; Respiration ; Respiratory distress syndrome ; Risk factors ; SARS-CoV-2 ; Search and rescue operations ; Severe acute respiratory syndrome coronavirus 2 ; Spike protein ; Staining ; Thrombosis ; Thymus gland ; Tungsten compounds</subject><ispartof>BMC infectious diseases, 2023-09, Vol.23 (1), p.1-576, Article 576</ispartof><rights>COPYRIGHT 2023 BioMed Central Ltd.</rights><rights>2023. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>BioMed Central Ltd., part of Springer Nature 2023</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c609t-890c7a0de8a8d7fbfa1fdead99cf42f8dc5f8f32daf0964cc9c9dabab21ec2893</citedby><cites>FETCH-LOGICAL-c609t-890c7a0de8a8d7fbfa1fdead99cf42f8dc5f8f32daf0964cc9c9dabab21ec2893</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC10478277/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2865358550?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,25753,27924,27925,37012,37013,44590,53791,53793</link.rule.ids></links><search><creatorcontrib>Kong, Jiangwei</creatorcontrib><creatorcontrib>Yang, Tengfei</creatorcontrib><creatorcontrib>Zhang, Fu</creatorcontrib><creatorcontrib>Liao, XinBiao</creatorcontrib><creatorcontrib>Du, Sihao</creatorcontrib><creatorcontrib>Yang, Xingan</creatorcontrib><creatorcontrib>Li, Dongri</creatorcontrib><title>Pulmonary fat embolism: a potentially new fatal complication of SARS-CoV-2 infection. A case report</title><title>BMC infectious diseases</title><description>So far, there have been more than 761 million confirmed cases of SARS-CoV-2 worldwide, with more than 6.8 million deaths. The most common direct causes of death for COVID-19 are diffuse alveolar injury and acute respiratory distress syndrome. Autopsy results have shown that 80-100% of COVID-19 patients have microthrombi which is 9 times higher than in patients with influenza. There are reported cases of fat embolism associated with Covid-19, but relevant epidemiological investigations and fatal cases of pulmonary fat embolism are lacking. In this report, we describe the first COVID-19 patient to die from pulmonary fat embolism. Pulmonary fat embolism may be another fatal complication of COVID-19 infection, and clinicians should pay more attention to it.</description><subject>Acute respiratory distress syndrome</subject><subject>Adrenal glands</subject><subject>Alveoli</subject><subject>Anticoagulants</subject><subject>Autopsies</subject><subject>Autopsy</subject><subject>Blood pressure</subject><subject>Blood vessels</subject><subject>C-reactive protein</subject><subject>Case Report</subject><subject>Case reports</subject><subject>COVID-19</subject><subject>Diagnosis</subject><subject>Disease transmission</subject><subject>Embolism</subject><subject>Embolisms</subject><subject>Epidemiology</subject><subject>Epithelial cells</subject><subject>Epithelium</subject><subject>Health aspects</subject><subject>Heart beat</subject><subject>Heart rate</subject><subject>Hemorrhage</subject><subject>Infections</subject><subject>Lungs</subject><subject>Medical screening</subject><subject>Nucleocapsids</subject><subject>Patient outcomes</subject><subject>Patients</subject><subject>Procalcitonin</subject><subject>Proteins</subject><subject>Pulmonary arteries</subject><subject>Pulmonary embolism</subject><subject>Pulmonary embolisms</subject><subject>Pulmonary fat embolism</subject><subject>Pulmonary microthromboembolism</subject><subject>Respiration</subject><subject>Respiratory distress syndrome</subject><subject>Risk factors</subject><subject>SARS-CoV-2</subject><subject>Search and rescue operations</subject><subject>Severe acute respiratory syndrome coronavirus 2</subject><subject>Spike protein</subject><subject>Staining</subject><subject>Thrombosis</subject><subject>Thymus gland</subject><subject>Tungsten compounds</subject><issn>1471-2334</issn><issn>1471-2334</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNqNkktv1DAUhSMEoqXwB1hZYkMXGfxKbLNBoxGPkSoVdaBb68aPwVUSD3YC9N_j6VTAIBbIC1v3fj7WPT5V9ZzgBSGyfZUJlULVmLIay6ZRNX9QnRIuSE0Z4w__OJ9UT3K-wZgISdXj6oSJthVEydPKfJz7IY6QbpGHCbmhi33Iw2sEaBcnN04B-v4Wje77vg89MnHY9cHAFOKIokeb5dWmXsXrmqIwemf29QVaIgPZoeR2MU1Pq0ce-uye3e9n1ed3bz-tPtQXl-_Xq-VFbVqsploqbARg6yRIK3zngXjrwCplPKdeWtN46Rm14LFquTHKKAsddJQ4Q6ViZ9X6oGsj3OhdCkMZS0cI-q4Q01ZDmoLpnRaY8s4aRbtGcYUttNQpKaRkTSesZEXrzUFrN3eDs6Y4kaA_Ej3ujOGL3sZvmmBeTBaiKLy8V0jx6-zypIeQjet7GF2cs6ayJQzTRrYFffEXehPnNBav9lTDmvK7-De1hTJBMTuWh81eVC9FyzjmnNFCLf5BlWXdEEwcnQ-lfnTh_OhCYSb3Y9rCnLNeb67-n728PmbpgTUp5pyc_2UewXqfX33Iry751Xf51Zz9BJ893vk</recordid><startdate>20230904</startdate><enddate>20230904</enddate><creator>Kong, Jiangwei</creator><creator>Yang, Tengfei</creator><creator>Zhang, Fu</creator><creator>Liao, XinBiao</creator><creator>Du, Sihao</creator><creator>Yang, Xingan</creator><creator>Li, Dongri</creator><general>BioMed Central Ltd</general><general>BioMed Central</general><general>BMC</general><scope>AAYXX</scope><scope>CITATION</scope><scope>IOV</scope><scope>ISR</scope><scope>3V.</scope><scope>7QL</scope><scope>7T2</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>20230904</creationdate><title>Pulmonary fat embolism: a potentially new fatal complication of SARS-CoV-2 infection. A case report</title><author>Kong, Jiangwei ; Yang, Tengfei ; Zhang, Fu ; Liao, XinBiao ; Du, Sihao ; Yang, Xingan ; Li, Dongri</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c609t-890c7a0de8a8d7fbfa1fdead99cf42f8dc5f8f32daf0964cc9c9dabab21ec2893</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Acute respiratory distress syndrome</topic><topic>Adrenal glands</topic><topic>Alveoli</topic><topic>Anticoagulants</topic><topic>Autopsies</topic><topic>Autopsy</topic><topic>Blood pressure</topic><topic>Blood vessels</topic><topic>C-reactive protein</topic><topic>Case Report</topic><topic>Case reports</topic><topic>COVID-19</topic><topic>Diagnosis</topic><topic>Disease transmission</topic><topic>Embolism</topic><topic>Embolisms</topic><topic>Epidemiology</topic><topic>Epithelial cells</topic><topic>Epithelium</topic><topic>Health aspects</topic><topic>Heart beat</topic><topic>Heart rate</topic><topic>Hemorrhage</topic><topic>Infections</topic><topic>Lungs</topic><topic>Medical screening</topic><topic>Nucleocapsids</topic><topic>Patient outcomes</topic><topic>Patients</topic><topic>Procalcitonin</topic><topic>Proteins</topic><topic>Pulmonary arteries</topic><topic>Pulmonary embolism</topic><topic>Pulmonary embolisms</topic><topic>Pulmonary fat embolism</topic><topic>Pulmonary microthromboembolism</topic><topic>Respiration</topic><topic>Respiratory distress syndrome</topic><topic>Risk factors</topic><topic>SARS-CoV-2</topic><topic>Search and rescue operations</topic><topic>Severe acute respiratory syndrome coronavirus 2</topic><topic>Spike protein</topic><topic>Staining</topic><topic>Thrombosis</topic><topic>Thymus gland</topic><topic>Tungsten compounds</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kong, Jiangwei</creatorcontrib><creatorcontrib>Yang, Tengfei</creatorcontrib><creatorcontrib>Zhang, Fu</creatorcontrib><creatorcontrib>Liao, XinBiao</creatorcontrib><creatorcontrib>Du, Sihao</creatorcontrib><creatorcontrib>Yang, Xingan</creatorcontrib><creatorcontrib>Li, Dongri</creatorcontrib><collection>CrossRef</collection><collection>Opposing Viewpoints Resource Center</collection><collection>Gale In Context: Science</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Virology and AIDS Abstracts</collection><collection>ProQuest Health and Medical</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><collection>DOAJ Directory of Open Access Journals</collection><jtitle>BMC infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kong, Jiangwei</au><au>Yang, Tengfei</au><au>Zhang, Fu</au><au>Liao, XinBiao</au><au>Du, Sihao</au><au>Yang, Xingan</au><au>Li, Dongri</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pulmonary fat embolism: a potentially new fatal complication of SARS-CoV-2 infection. A case report</atitle><jtitle>BMC infectious diseases</jtitle><date>2023-09-04</date><risdate>2023</risdate><volume>23</volume><issue>1</issue><spage>1</spage><epage>576</epage><pages>1-576</pages><artnum>576</artnum><issn>1471-2334</issn><eissn>1471-2334</eissn><abstract>So far, there have been more than 761 million confirmed cases of SARS-CoV-2 worldwide, with more than 6.8 million deaths. The most common direct causes of death for COVID-19 are diffuse alveolar injury and acute respiratory distress syndrome. Autopsy results have shown that 80-100% of COVID-19 patients have microthrombi which is 9 times higher than in patients with influenza. There are reported cases of fat embolism associated with Covid-19, but relevant epidemiological investigations and fatal cases of pulmonary fat embolism are lacking. In this report, we describe the first COVID-19 patient to die from pulmonary fat embolism. Pulmonary fat embolism may be another fatal complication of COVID-19 infection, and clinicians should pay more attention to it.</abstract><cop>London</cop><pub>BioMed Central Ltd</pub><pmid>37667198</pmid><doi>10.1186/s12879-023-08559-4</doi><oa>free_for_read</oa></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1471-2334 |
ispartof | BMC infectious diseases, 2023-09, Vol.23 (1), p.1-576, Article 576 |
issn | 1471-2334 1471-2334 |
language | eng |
recordid | cdi_doaj_primary_oai_doaj_org_article_7024bdc92b59490da62e9878835b7d83 |
source | PubMed (Medline); Publicly Available Content Database |
subjects | Acute respiratory distress syndrome Adrenal glands Alveoli Anticoagulants Autopsies Autopsy Blood pressure Blood vessels C-reactive protein Case Report Case reports COVID-19 Diagnosis Disease transmission Embolism Embolisms Epidemiology Epithelial cells Epithelium Health aspects Heart beat Heart rate Hemorrhage Infections Lungs Medical screening Nucleocapsids Patient outcomes Patients Procalcitonin Proteins Pulmonary arteries Pulmonary embolism Pulmonary embolisms Pulmonary fat embolism Pulmonary microthromboembolism Respiration Respiratory distress syndrome Risk factors SARS-CoV-2 Search and rescue operations Severe acute respiratory syndrome coronavirus 2 Spike protein Staining Thrombosis Thymus gland Tungsten compounds |
title | Pulmonary fat embolism: a potentially new fatal complication of SARS-CoV-2 infection. A case report |
url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T18%3A02%3A25IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Pulmonary%20fat%20embolism:%20a%20potentially%20new%20fatal%20complication%20of%20SARS-CoV-2%20infection.%20A%20case%20report&rft.jtitle=BMC%20infectious%20diseases&rft.au=Kong,%20Jiangwei&rft.date=2023-09-04&rft.volume=23&rft.issue=1&rft.spage=1&rft.epage=576&rft.pages=1-576&rft.artnum=576&rft.issn=1471-2334&rft.eissn=1471-2334&rft_id=info:doi/10.1186/s12879-023-08559-4&rft_dat=%3Cgale_doaj_%3EA763404432%3C/gale_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c609t-890c7a0de8a8d7fbfa1fdead99cf42f8dc5f8f32daf0964cc9c9dabab21ec2893%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2865358550&rft_id=info:pmid/37667198&rft_galeid=A763404432&rfr_iscdi=true |