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The outcomes of cataract surgery in eyes with Fuchs uveitis

Background To evaluate clinical results in eyes undergoing phacoemulsification intraocular lens (IOL) implantation due to Fuchs , uveitis (FU) related complicated cataract. Methods Post-surgical outcomes of 56 eyes of 55 FU patients were evaluated retrospectively. Three groups were formed according...

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Published in:Journal of ophthalmic inflammation and infection 2023-02, Vol.13 (1), p.4-4, Article 4
Main Authors: Özdamar Erol, Yasemin, Özdemir Yalçınsoy, Kübra, Özdal, Pınar
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description Background To evaluate clinical results in eyes undergoing phacoemulsification intraocular lens (IOL) implantation due to Fuchs , uveitis (FU) related complicated cataract. Methods Post-surgical outcomes of 56 eyes of 55 FU patients were evaluated retrospectively. Three groups were formed according to the IOL model: hydrophilic SAF6125 (Optima fold) acrylic, hydrophobic SN60AT (Alcon), and hydrophobic AAB00 (Abbott). Postoperative posterior capsular opacification (PCO) development and PCO development time, neodymium number: YAG laser posterior capsulotomy rate, giant cell (GC) deposition on the IOL, and the development time of GC deposits were compared among the groups. All patients were followed postoperatively on the 1 st day, 1 st week, 2 nd and 6 th weeks, and then at 3-month intervals. Results The hydrophilic SAF6125 IOL was implanted in 10 eyes, hydrophobic SN60AT in 24 eyes and AAB00 IOL in 22 eyes. The mean postoperative follow-up time was 34.1 ± 30.1 (6-144) months. PCO developed in 7 eyes (70%) in the hydrophilic SAF6125 group, 17 eyes (70.8%) in the hydrophobic SN60AT and 13 eyes (59.1%) in the AAB00 group. There was no statistically significant difference among the three IOL groups in the PCO development, the PCO development time and YAG laser capsulotomy rates ( P  = 0.674, P  = 0.111, and P  = 0.507, respectively). The PCO development time was significantly longer in the hydrophobic SN60AT than AAB00 group ( P  = 0.027). GC deposits were detected in 3 eyes (30%) in the hydrophilic SAF6125 group, 7 eyes (29.1%) in the hydrophobic SN60AT and 3 eyes (13.6%) in the AAB00 group. GC deposition and the development time of GC deposits were similar among the three IOL groups ( P  = 0.575, P  = 0.804). At the final follow-up, BCVA was ≥ 20/40 in 41 eyes (73.2%). Conclusion The GC deposits and PCO development were the most important problems in these eyes with hydrophilic or hydrophobic IOLs despite good visual and postoperative results. New developments are needed in terms of IOL design or content in eyes with FU.
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Methods Post-surgical outcomes of 56 eyes of 55 FU patients were evaluated retrospectively. Three groups were formed according to the IOL model: hydrophilic SAF6125 (Optima fold) acrylic, hydrophobic SN60AT (Alcon), and hydrophobic AAB00 (Abbott). Postoperative posterior capsular opacification (PCO) development and PCO development time, neodymium number: YAG laser posterior capsulotomy rate, giant cell (GC) deposition on the IOL, and the development time of GC deposits were compared among the groups. All patients were followed postoperatively on the 1 st day, 1 st week, 2 nd and 6 th weeks, and then at 3-month intervals. Results The hydrophilic SAF6125 IOL was implanted in 10 eyes, hydrophobic SN60AT in 24 eyes and AAB00 IOL in 22 eyes. The mean postoperative follow-up time was 34.1 ± 30.1 (6-144) months. PCO developed in 7 eyes (70%) in the hydrophilic SAF6125 group, 17 eyes (70.8%) in the hydrophobic SN60AT and 13 eyes (59.1%) in the AAB00 group. There was no statistically significant difference among the three IOL groups in the PCO development, the PCO development time and YAG laser capsulotomy rates ( P  = 0.674, P  = 0.111, and P  = 0.507, respectively). The PCO development time was significantly longer in the hydrophobic SN60AT than AAB00 group ( P  = 0.027). GC deposits were detected in 3 eyes (30%) in the hydrophilic SAF6125 group, 7 eyes (29.1%) in the hydrophobic SN60AT and 3 eyes (13.6%) in the AAB00 group. GC deposition and the development time of GC deposits were similar among the three IOL groups ( P  = 0.575, P  = 0.804). At the final follow-up, BCVA was ≥ 20/40 in 41 eyes (73.2%). Conclusion The GC deposits and PCO development were the most important problems in these eyes with hydrophilic or hydrophobic IOLs despite good visual and postoperative results. New developments are needed in terms of IOL design or content in eyes with FU.</description><identifier>ISSN: 1869-5760</identifier><identifier>EISSN: 1869-5760</identifier><identifier>DOI: 10.1186/s12348-022-00320-3</identifier><identifier>PMID: 36780022</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Biocompatibility ; Cataract ; Cataracts ; Cornea ; Diabetic retinopathy ; Edema ; Eye surgery ; Fuchs’ Uveitis ; Hospitals ; Infections ; Inflammation ; Intraocular lenses ; Lasers ; Medicine ; Medicine &amp; Public Health ; Open access publishing ; Ophthalmology ; Phacoemulsification ; Steroids ; Surgical outcomes</subject><ispartof>Journal of ophthalmic inflammation and infection, 2023-02, Vol.13 (1), p.4-4, Article 4</ispartof><rights>The Author(s) 2023</rights><rights>2023. The Author(s).</rights><rights>The Author(s) 2023. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). 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Methods Post-surgical outcomes of 56 eyes of 55 FU patients were evaluated retrospectively. Three groups were formed according to the IOL model: hydrophilic SAF6125 (Optima fold) acrylic, hydrophobic SN60AT (Alcon), and hydrophobic AAB00 (Abbott). Postoperative posterior capsular opacification (PCO) development and PCO development time, neodymium number: YAG laser posterior capsulotomy rate, giant cell (GC) deposition on the IOL, and the development time of GC deposits were compared among the groups. All patients were followed postoperatively on the 1 st day, 1 st week, 2 nd and 6 th weeks, and then at 3-month intervals. Results The hydrophilic SAF6125 IOL was implanted in 10 eyes, hydrophobic SN60AT in 24 eyes and AAB00 IOL in 22 eyes. The mean postoperative follow-up time was 34.1 ± 30.1 (6-144) months. PCO developed in 7 eyes (70%) in the hydrophilic SAF6125 group, 17 eyes (70.8%) in the hydrophobic SN60AT and 13 eyes (59.1%) in the AAB00 group. There was no statistically significant difference among the three IOL groups in the PCO development, the PCO development time and YAG laser capsulotomy rates ( P  = 0.674, P  = 0.111, and P  = 0.507, respectively). The PCO development time was significantly longer in the hydrophobic SN60AT than AAB00 group ( P  = 0.027). GC deposits were detected in 3 eyes (30%) in the hydrophilic SAF6125 group, 7 eyes (29.1%) in the hydrophobic SN60AT and 3 eyes (13.6%) in the AAB00 group. GC deposition and the development time of GC deposits were similar among the three IOL groups ( P  = 0.575, P  = 0.804). At the final follow-up, BCVA was ≥ 20/40 in 41 eyes (73.2%). Conclusion The GC deposits and PCO development were the most important problems in these eyes with hydrophilic or hydrophobic IOLs despite good visual and postoperative results. 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Methods Post-surgical outcomes of 56 eyes of 55 FU patients were evaluated retrospectively. Three groups were formed according to the IOL model: hydrophilic SAF6125 (Optima fold) acrylic, hydrophobic SN60AT (Alcon), and hydrophobic AAB00 (Abbott). Postoperative posterior capsular opacification (PCO) development and PCO development time, neodymium number: YAG laser posterior capsulotomy rate, giant cell (GC) deposition on the IOL, and the development time of GC deposits were compared among the groups. All patients were followed postoperatively on the 1 st day, 1 st week, 2 nd and 6 th weeks, and then at 3-month intervals. Results The hydrophilic SAF6125 IOL was implanted in 10 eyes, hydrophobic SN60AT in 24 eyes and AAB00 IOL in 22 eyes. The mean postoperative follow-up time was 34.1 ± 30.1 (6-144) months. PCO developed in 7 eyes (70%) in the hydrophilic SAF6125 group, 17 eyes (70.8%) in the hydrophobic SN60AT and 13 eyes (59.1%) in the AAB00 group. There was no statistically significant difference among the three IOL groups in the PCO development, the PCO development time and YAG laser capsulotomy rates ( P  = 0.674, P  = 0.111, and P  = 0.507, respectively). The PCO development time was significantly longer in the hydrophobic SN60AT than AAB00 group ( P  = 0.027). GC deposits were detected in 3 eyes (30%) in the hydrophilic SAF6125 group, 7 eyes (29.1%) in the hydrophobic SN60AT and 3 eyes (13.6%) in the AAB00 group. GC deposition and the development time of GC deposits were similar among the three IOL groups ( P  = 0.575, P  = 0.804). At the final follow-up, BCVA was ≥ 20/40 in 41 eyes (73.2%). Conclusion The GC deposits and PCO development were the most important problems in these eyes with hydrophilic or hydrophobic IOLs despite good visual and postoperative results. New developments are needed in terms of IOL design or content in eyes with FU.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>36780022</pmid><doi>10.1186/s12348-022-00320-3</doi><tpages>1</tpages><oa>free_for_read</oa></addata></record>
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subjects Biocompatibility
Cataract
Cataracts
Cornea
Diabetic retinopathy
Edema
Eye surgery
Fuchs’ Uveitis
Hospitals
Infections
Inflammation
Intraocular lenses
Lasers
Medicine
Medicine & Public Health
Open access publishing
Ophthalmology
Phacoemulsification
Steroids
Surgical outcomes
title The outcomes of cataract surgery in eyes with Fuchs uveitis
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