Associations between cardiorespiratory fitness and weight loss in patients with severe obesity undergoing an intensive lifestyle intervention program: retrospective cohort study

• Published in: BMC endocrine disorders 2019-07, Vol.19 (1), p.69-69, Article 69
• Main Authors: Berge, Jarle, Støren, Øyvind, Hertel, Jens K, Gjevestad, Espen, Småstuen, Milada Cvancarova, Hjelmesæth, Jøran
• Format: Article
• Language: English
• Subjects: Body Mass Index; Body weight loss; Cardiorespiratory Fitness; Cardiovascular physiology; Care and treatment; Cohort analysis; Energy; Energy Metabolism; Exercise; Exercise physiology; Fitness equipment; Fitness training programs; Health aspects; Heart rate; Humans; Interval training; Intervention; Life Style; Lifestyle intervention; Lifestyles; Obesity; Obesity, Morbid; Oxygen consumption; Patient outcomes; Patients; Physical fitness; Physiology; Rehabilitation; Respiratory system; Retrospective Studies; Severe obesity; Studies; VO2max; Weight change; Weight control; Weight Loss
• ISSN: 1472-6823; 1472-6823
• DOI: 10.1186/s12902-019-0394-z

To assess the association between cardiorespiratory fitness (CRF) and weight changes in treatment seeking patients with severe obesity who underwent a 1-year intensive lifestyle intervention (ILI) program. Retrospective cohort study conducted at a tertiary care outpatient rehabilitation center from November 1, 2013 through January 1, 2017. CRF was measured as maximal oxygen consumption during a maximal oxygen uptake (VO ) test on a treadmill or bicycle at baseline and after 3 months. A total of 180 patients had a baseline mean (SD) BMI 41.1 (4.8) kg/m and CRF of 79.4 (14.9) mL·kg ·min . Patients with a baseline CRF above median achieved a greater 3-month and 1-year weight loss compared with patients with CRF below median; mean (95% CI) 2.5 kg (1.3, 3.8) and 4.0 kg (0.8, 7.2), respectively. In addition, patients with 3-month changes of CRF above median had 4.0 kg (0.9, 7.1) greater weight loss at 1-year follow-up than those below median. Among patients with severe obesity who underwent a 1-year ILI program, higher baseline CRF was associated with significantly larger weight loss after 3 months and 1 year. In addition, those with higher initial 3-month CRF changes had greater weight loss at 1 year. Retrospectively registered in Regional Committees for Medical and Health Research Ethics (REC) south east September 22, 2016 (2016/1414) and clinicaltials.gov August 13, 2018 (identifier: NCT03593798 ).