Heterologous protein production in the moss Physcomitrella patens

Over the last decades plants have been used for the heterologous production of pharmaceuticals, industrial enzymes and edible vaccines. The moss Physcomitrella patens is considered as an experimental model of choice for basic molecular, cytological and developmental questions in plant biology, as we...

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Bibliographic Details
Published in:Vaccimonitor 2017-08, Vol.26 (2), p.66-69
Main Authors: Evelien Cools, Patrick Van Dijck, Nelson Avonce
Format: Article
Language:English
Subjects:
bioreactor
moss
osmotin
recombinant protein
Online Access:Get full text
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Summary:Over the last decades plants have been used for the heterologous production of pharmaceuticals, industrial enzymes and edible vaccines. The moss Physcomitrella patens is considered as an experimental model of choice for basic molecular, cytological and developmental questions in plant biology, as well as an outstanding plant model system for heterologous protein production. Here we use P. patens to produce osmotin, a tobacco protein with fungicidal properties. We have generated a transgenic plant able to synthesize and secrete a biologically active osmotin protein.
ISSN:1025-028X
1025-0298