Preimplantation Genetic Screening: A Practical Guide

The past several decades have seen tremendous advances in the field of medical genetics. The application of genetic technologies to the field of reproductive medicine has ushered in a new era of medicine that is likely to greatly expand in the coming years. Concurrent with an in vitro fertilization...

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Bibliographic Details
Published in:Clinical Medicine Insights: Reproductive Health 2013-02, Vol.2013 (2013), p.37-42
Main Authors: Brezina, Paul R., Ke, Raymond W., Kutteh, William H.
Format: Article
Language:English
Subjects:
Chromosomes
Embryonic development
Genetic screening
Medical genetics
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Summary:The past several decades have seen tremendous advances in the field of medical genetics. The application of genetic technologies to the field of reproductive medicine has ushered in a new era of medicine that is likely to greatly expand in the coming years. Concurrent with an in vitro fertilization (IVF) cycle, it is now possible to obtain a cellular biopsy from a developing embryo and genetically evaluate this sample with increasing sophistication and detail. Preimplantation genetic screening (PGS) is the practice of determining the presence of aneuploidy (either too many or too few chromosomes) in a developing embryo. However, how and in whom PGS should be offered is a topic of much debate.
ISSN:1179-5581
1179-5581
DOI:10.4137/CMRH.S10852