Preparation and in Vitro Bioactivity of Micron-sized Bioactive Glass Particles Using Spray Drying Method

In recent years, bioactive glasses (BGs) have attracted enormous attention with their superior bioactivity, non-toxicity and degradability. Owing to their properties, they have been applied in various biological applications. In the present work, we demonstrated that micron-sized BGs can be prepared...

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Bibliographic Details
Published in:Applied sciences 2019-01, Vol.9 (1), p.19
Main Authors: Chou, Yu-Jen, Hsiao, Chih-Wei, Tsou, Nien-Ti, Wu, Meng-Huang, Shih, Shao-Ju
Format: Article
Language:English
Subjects:
bioactive glass
Biocompatibility
Bioglass
Biological activity
Biomedical materials
Body fluids
Bones
Contamination
Degradability
Drying
Hydroxyapatite
In vitro methods and tests
Ion beams
Mass production
Materials science
Mechanical properties
Methods
Morphology
Nitrates
Particle size
Phase composition
Radioisotopes
Scanning electron microscopy
Sol-gel processes
Spray drying
spray drying method
Surgical implants
Toxicity
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Summary:In recent years, bioactive glasses (BGs) have attracted enormous attention with their superior bioactivity, non-toxicity and degradability. Owing to their properties, they have been applied in various biological applications. In the present work, we demonstrated that micron-sized BGs can be prepared with a spray drying method. This technique offers the advantages of low contamination and the ability of mass production, in contrast to the two major synthetic methods, conventional glass-melting and sol-gel, previously used for preparation of BGs. Characterizations of phase composition, morphology and specific surface area of spray dried BG powders were carried out and bioactivity was examined in vitro with respect to the ability to form a hydroxyapatite layer on the surface of the particles after they were immersed in simulated body fluid.
ISSN:2076-3417
2076-3417
DOI:10.3390/app9010019