ABioTrans: A Biostatistical Tool for Transcriptomics Analysis

Here we report a bio-statistical/informatics tool, ABioTrans, developed in R for gene expression analysis. The tool allows the user to directly read RNA-Seq data files deposited in the Gene Expression Omnibus or GEO database. Operated using any web browser application, ABioTrans provides easy option...

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Bibliographic Details
Published in:Frontiers in genetics 2019, Vol.10, p.499-499
Main Authors: Zou, Yutong, Bui, Thuy Tien, Selvarajoo, Kumar
Format: Article
Language:English
Subjects:
correlation
DEG (differentially expressed genes)
entropy
Genetics
noise
RNA-seq
transcriptomics
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Description
Summary:Here we report a bio-statistical/informatics tool, ABioTrans, developed in R for gene expression analysis. The tool allows the user to directly read RNA-Seq data files deposited in the Gene Expression Omnibus or GEO database. Operated using any web browser application, ABioTrans provides easy options for multiple statistical distribution fitting, Pearson and Spearman rank correlations, PCA, -means and hierarchical clustering, differential expression (DE) analysis, Shannon entropy and noise (square of coefficient of variation) analyses, as well as Gene ontology classifications.
ISSN:1664-8021
1664-8021
DOI:10.3389/fgene.2019.00499