Effects of sample handling on the stability of interleukin-6 in patients with breast neoplasms

To investigate the influence of preservation methods and processes on the plasma interleukin-6 (IL-6) stability.Lithium-heparin plasma was collected from female patients: 32 female patients with invasive breast neoplasms and 20 healthy females. Each sample was divided into three tubes. Samples were...

Full description

Saved in:
Bibliographic Details
Published in:Journal of laboratory medicine 2022-04, Vol.46 (2), p.115-119
Main Authors: Wang, Yunxiu, Wang, Baiye, She, Lanhui, Wang, Jijuan, Chen, Yingting, Huang, Di, Han, Guang, Lu, Miaolian, Wu, Xiaobin, Wan, Zemin, He, Min, Ke, Peifeng, Huang, Xianzhang, Liu, Hongcan
Format: Article
Language:English
Subjects:
Breast
Cytokines
Females
Heparin
Interleukin 6
interleukin-6 (il-6)
Interleukins
Lithium
Neoplasms
pre-analytical
Stability
Storage
Storage conditions
storage time
temperature
Tubes
Tumors
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To investigate the influence of preservation methods and processes on the plasma interleukin-6 (IL-6) stability.Lithium-heparin plasma was collected from female patients: 32 female patients with invasive breast neoplasms and 20 healthy females. Each sample was divided into three tubes. Samples were stored at different temperatures or at different times. The concentration of IL-6 was detected.IL-6 levels in patients were not altered significantly compared to the control group after storage at 4 °C or 25 °C for 12 h. However, IL-6 levels were significantly higher compared to controls (p
ISSN:2567-9430
0342-3026
2567-9449
1439-0477
DOI:10.1515/labmed-2020-0155