Late follow-up of peripheral neural decompression in leprosy: functional and clinical outcomes

ABSTRACT Background: Peripheral neural surgical decompression (PNSD) is used as a complementary therapy to the clinical treatment of neuritis to preserve neural function. Objective: To evaluate the long-term (≥ 1 year) clinical and functional results for PNSD in leprosy neuritis. Methods: This cross...

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Published in:Arquivos de neuro-psiquiatria 2021-08, Vol.79 (8), p.716-723
Main Authors: Tiago, Liliane Marques de Pinho, Barbosa, Maria Fernanda Ferreira, Santos, Diogo Fernandes dos, Faria, Adelmo Divino, Gonçalves, Maria Aparecida, Costa, Adeilson Vieira, Goulart, Isabela Maria Bernardes
Format: Article
Language:English
Subjects:
Corticosteroids
Decompression
Decompression, Surgical
Epidemiology
Leprosy
Nerves
Neuralgia
Neuritis
NEUROSCIENCES
Pain
Patients
Peripheral Nerves
Peripheral neuropathy
Prednisone
PSYCHIATRY
Statistical analysis
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Summary:ABSTRACT Background: Peripheral neural surgical decompression (PNSD) is used as a complementary therapy to the clinical treatment of neuritis to preserve neural function. Objective: To evaluate the long-term (≥ 1 year) clinical and functional results for PNSD in leprosy neuritis. Methods: This cross-sectional study included leprosy patients who were in late postoperative period (LPO) of surgical decompression of ulnar, median, tibial, and fibular nerves. Socioeconomic, epidemiological, and clinical data were collected. The following instruments were used in this evaluation: visual analogue pain scale (VAS), Douleur Neuropathique en 4 Questions (DN4), SALSA scale, and simplified neurological assessment protocol. The preoperative (PrO) and 180-day postoperative (PO180) results were compared. Results: We evaluated 246 nerves from 90 patients: 56.6% were on multidrug therapy (MDT) and 43.3% discharged from MDT. Motor scores and pain intensity showed statistically significant improvement (p
ISSN:0004-282X
1678-4227
1678-4227
DOI:10.1590/0004-282X-ANP-2020-0032