Aptamers: A Cutting-Edge Approach for Gram-Negative Bacterial Pathogen Identification

Early and accurate diagnoses of pathogenic microorganisms is essential to correctly identify diseases, treating infections, and tracking disease outbreaks associated with microbial infections, to develop precautionary measures that allow a fast and effective response in epidemics and pandemics, thus...

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Bibliographic Details
Published in:International journal of molecular sciences 2024-01, Vol.25 (2), p.1257
Main Authors: Córdova-Espinoza, María Guadalupe, González-Vázquez, Rosa, Barron-Fattel, Rolando Rafik, Gónzalez-Vázquez, Raquel, Vargas-Hernández, Marco Antonio, Albores-Méndez, Exsal Manuel, Esquivel-Campos, Ana Laura, Mendoza-Pérez, Felipe, Mayorga-Reyes, Lino, Gutiérrez-Nava, María Angélica, Medina-Quero, Karen, Escamilla-Gutiérrez, Alejandro
Format: Article
Language:English
Subjects:
aptamers
Aptamers, Nucleotide
Bacteria
Biosensors
Campylobacter
Communicable Diseases
Design
Development and progression
Disease
Drug delivery systems
Food contamination & poisoning
Gram-negative bacteria
Gram-Negative Bacteria - genetics
Health aspects
Humans
Infection
Infections
Ligands
Microorganisms
Monoclonal antibodies
Nucleic acids
pathogen identification
Pathogens
Public health
SELEX
SELEX Aptamer Technique
Tazobactam
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Summary:Early and accurate diagnoses of pathogenic microorganisms is essential to correctly identify diseases, treating infections, and tracking disease outbreaks associated with microbial infections, to develop precautionary measures that allow a fast and effective response in epidemics and pandemics, thus improving public health. Aptamers are a class of synthetic nucleic acid molecules with the potential to be used for medical purposes, since they can be directed towards any target molecule. Currently, the use of aptamers has increased because they are a useful tool in the detection of specific targets. We present a brief review of the use of aptamers to detect and identify bacteria or even some toxins with clinical importance. This work describes the advances in the technology of aptamers, with the purpose of providing knowledge to develop new aptamers for diagnoses and treatment of different diseases caused by infectious microorganisms.
ISSN:1422-0067
1661-6596
1422-0067
DOI:10.3390/ijms25021257