Paraganglioma-induced pheochromocytoma crisis successfully treated by veno-arterial extracorporeal membrane oxygenation: a case report

Pheochromocytoma crisis is rare but potentially fatal if not recognized early and properly managed. Here, a woman in her 20s with a paraganglioma-induced pheochromocytoma crisis, who was successfully treated by veno-arterial extracorporeal membrane oxygenation (VA-ECMO) and interval tumor resection,...

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Bibliographic Details
Published in:Journal of international medical research 2024-09, Vol.52 (9), p.3000605241270655
Main Authors: Tong, Mengqi, Wang, Shan, Bai, Ying, Wang, Hao
Format: Article
Language:English
Subjects:
Adrenal Gland Neoplasms - complications
Adrenal Gland Neoplasms - diagnosis
Adrenal Gland Neoplasms - surgery
Adult
Case Report and Case Series
Extracorporeal Membrane Oxygenation
Female
Humans
Paraganglioma - complications
Paraganglioma - surgery
Paraganglioma - therapy
Pheochromocytoma - complications
Pheochromocytoma - pathology
Pheochromocytoma - surgery
Tomography, X-Ray Computed
Treatment Outcome
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Summary:Pheochromocytoma crisis is rare but potentially fatal if not recognized early and properly managed. Here, a woman in her 20s with a paraganglioma-induced pheochromocytoma crisis, who was successfully treated by veno-arterial extracorporeal membrane oxygenation (VA-ECMO) and interval tumor resection, is described. In July 2022, the patient was brought to hospital with a complaint of sudden-onset of palpitations with vomiting. The patient developed cardiorespiratory failure with hypoxia. Computed tomography scan showed pulmonary oedema and a mass anterior to the inferior vena cava. She was transferred to the intensive care unit and treated with VA-ECMO. The patient’s ECMO was withdrawn after 6 days without any complications. After hemodynamic stabilization, the patient underwent tumor resection 4 months later. The postoperative course was uneventful and she was discharged on postoperative day 7. Histopathological analysis confirmed a paraganglioma. VA-ECMO may play a significant role in saving lives and providing time for accurate diagnosis and specific treatment of a patient with pheochromocytoma crisis. Appropriate individual management can help avoid the occurrence of ECMO complications.
ISSN:0300-0605
1473-2300
1473-2300
DOI:10.1177/03000605241270655