Lymphoplasmacytic and eosinophilic enteritis with or without globule leukocyte hyperplasia in 4 goats

Four, mature, client‐owned goats were presented to referral hospitals for recurrent diarrhea despite treatment for intestinal parasitism. Common clinical findings included diarrhea, poor condition, neutrophilia, and hypoalbuminemia. Testing for common infectious causes of diarrhea in goats was negat...

Full description

Saved in:
Bibliographic Details
Published in:Journal of veterinary internal medicine 2021-05, Vol.35 (3), p.1620-1625
Main Authors: Pitel, Mariya O., Heller, Meera C., Roberson, Jerry R., McKenzie, Erica C., Sinnott, Devinn M., Affolter, Verena K.
Format: Article
Language:English
Subjects:
Abdomen
Anemia
Biopsy
caprine
Case Report
Diarrhea
Drug dosages
Edema
Feces
FOOD AND FIBER
Hyperglycemia
Hyperplasia
hypoalbuminemia
Inflammation
inflammatory bowel disease
Laparotomy
Lymphatic system
Manures
Plasma
Small intestine
Trace elements
Ultrasonic imaging
weight loss
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Four, mature, client‐owned goats were presented to referral hospitals for recurrent diarrhea despite treatment for intestinal parasitism. Common clinical findings included diarrhea, poor condition, neutrophilia, and hypoalbuminemia. Testing for common infectious causes of diarrhea in goats was negative. Ultrasonography and computed tomography in 2 cases was suggestive of enteritis, including thickened intestinal walls and fluid filled, dilated small intestines, respectively. Lymphoplasmacytic and eosinophilic enteritis (LEE) was ultimately diagnosed on intestinal biopsy histopathology based on the presence of small intestinal villous blunting and increased numbers of lymphocytes and eosinophils predominantly within the lamina propria. Numerous globule leukocytes were also noted on histopathology in 3 cases. All goats responded favorably to corticosteroid treatment with weight gain and resolution of diarrhea and clinicopathologic abnormalities. Relapses occurred, and complete cure was difficult to achieve. Reported in other species, this series describes the clinical presentation, diagnosis, and treatment of LEE in adult goats.
ISSN:0891-6640
1939-1676
DOI:10.1111/jvim.16110