Effectiveness of lotilaner on furuncular myiasis in dogs naturally infested with Dermatobia hominis (Diptera: Cuterebridae)

An evaluation was made of the larvicidal efficacy of lotilaner (Credeli®) in the treatment of dogs naturally infested with Dermatobia hominis larvae. A total of 12 dogs presenting at least three live D. hominis larvae were medicated. The animals were medicated orally with a single dose of no less th...

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Published in:Revista brasileira de parasitologia veterinaria 2024, Vol.33 (3), p.e009524
Main Authors: Tortoriello, Rafaella, Christ, Luisa Xavier, Marques, Victoria Caroline de Almeida, Martins, Bruna Sampaio, Fernandes, Julio Israel
Format: Article
Language:English
Subjects:
Animals
Dermatobia hominis
Diptera - drug effects
Dog Diseases - drug therapy
Dog Diseases - parasitology
Dogs
Female
Insecticides - administration & dosage
isoxazolines
Larva - drug effects
lotilaner
Male
Myiasis - diagnosis
Myiasis - drug therapy
Myiasis - parasitology
Myiasis - veterinary
Oxazoles
PARASITOLOGY
Thiophenes
treatment
Treatment Outcome
VETERINARY SCIENCES
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Summary:An evaluation was made of the larvicidal efficacy of lotilaner (Credeli®) in the treatment of dogs naturally infested with Dermatobia hominis larvae. A total of 12 dogs presenting at least three live D. hominis larvae were medicated. The animals were medicated orally with a single dose of no less than 20 mg/kg lotilaner. After drug administration, the animals remained at their homes, and observations were made to verify the larvicidal effect 6 hours after treatment. Live larvae were considered any parasite that exhibited motility after removal. For each animal was using the formula: 100 x [(total of live larvae before treatment - total live larvae after treatment) /total of live larvae before treatment] as criteria for evaluating lotilaner efficacy. A total of 98 larvae were counted in 12 dogs, with an average of 8.1 larvae per animal. The effectiveness of lotilaner was 80.6%. Nineteen larvae were found alive, albeit presenting hypomobility and lethargic behavior. However, note that the evaluation was performed just six hours after administration of the drug. Lotilaner administered orally in a single dose of 20 mg/kg showed 80.6% efficacy six hours after treating dogs naturally infested with D. hominis.
ISSN:1984-2961
1984-2961
DOI:10.1590/S1984-29612024054.