Cohort profile: why do people keep hurting their back?

Low back pain (LBP) is one of the most disabling and costly conditions worldwide. It remains unclear why many individuals experience persistent and recurrent symptoms after an acute episode whereas others do not. A longitudinal cohort study was established to address this problem. We aimed to; (1) e...

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Bibliographic Details
Published in:BMC research notes 2020-11, Vol.13 (1), p.538-538, Article 538
Main Authors: Klyne, David M, van den Hoorn, Wolbert, Barbe, Mary F, Cholewicki, Jacek, M Hall, Leanne, Khan, Asaduzzaman, Meroni, Roberto, Moseley, G Lorimer, Nicholas, Michael, O'Sullivan, Lee, Park, Rachel, Russell, Glen, Sterling, Michele, Hodges, Paul W
Format: Article
Language:English
Subjects:
Acute to chronic
Behavioural factors
Biological factors
Cohort Studies
Data collection
Diagnosis
Disabled Persons
Humans
Laboratories
Longitudinal Studies
Low Back Pain
Low back pain (LBP)
Pain
Pain Measurement
Patient outcomes
Psychological factors
Questionnaires
Research Note
Risk factors
Sleep
Social factors
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Summary:Low back pain (LBP) is one of the most disabling and costly conditions worldwide. It remains unclear why many individuals experience persistent and recurrent symptoms after an acute episode whereas others do not. A longitudinal cohort study was established to address this problem. We aimed to; (1) evaluate whether promising and potentially modifiable biological, psychological, social and behavioural factors, along with their possible interactions, predict LBP outcome after an acute episode; (2) compare these factors between individuals with and without acute LBP; and (3) evaluate the time-course of changes in these factors from LBP onset. This paper outlines the methodology and compares baseline characteristics between acute LBP and control, and LBP participants with and without follow-up. 133 individuals with acute LBP and 74 pain-free individuals participated. Bio-psycho-social and behavioural measures were collected at baseline and 3-monthly for 12 months (LBP) or 3 months (control). Pain and disability were recorded fortnightly. Baseline characteristics were mostly similar between those who did and did not return for follow-up. Initial analyses of this cohort have revealed important insights into the pathways involved in acute-to-chronic LBP. These and future findings will provide new targets for treatment and prevention of persistent and recurrent LBP.
ISSN:1756-0500
1756-0500
DOI:10.1186/s13104-020-05356-z