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Giant primary ovarian fibrosarcoma: Case report and review of pitfalls
Primary ovarian fibrosarcomas are very uncommon neoplasms; less than one hundred cases have been reported. Diagnosis can be difficult to establish and other similar appearing mesenchymal lesions must be ruled out. A 23 year old nulliparous woman presented with a huge right ovarian tumor (25 × 17 × 1...
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Published in: | Journal of cytology 2012-10, Vol.29 (4), p.255-257 |
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creator | Ray, Sumit Biswas, Biplab K Mukhopadhyay, Subhalakshmi |
description | Primary ovarian fibrosarcomas are very uncommon neoplasms; less than one hundred cases have been reported. Diagnosis can be difficult to establish and other similar appearing mesenchymal lesions must be ruled out. A 23 year old nulliparous woman presented with a huge right ovarian tumor (25 × 17 × 12 cm). Ultrasonography guided aspiration was performed and a strong possibility of fibrosarcoma was suggested based on cytomorphological findings. No epithelial element was noted. She underwent surgical excision which confirmed the diagnosis of primary ovarian fibrosarcoma (the largest till date to our knowledge). Immunohistochemical analyses showed vimentin and CD 34 positivity. We speculate that ovarian fibrosarcoma at the preoperative examination might be considered in the differential diagnosis whenever a unilateral, heterogeneous, largely round solid ovarian lesion is detected. |
doi_str_mv | 10.4103/0970-9371.103946 |
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Diagnosis can be difficult to establish and other similar appearing mesenchymal lesions must be ruled out. A 23 year old nulliparous woman presented with a huge right ovarian tumor (25 × 17 × 12 cm). Ultrasonography guided aspiration was performed and a strong possibility of fibrosarcoma was suggested based on cytomorphological findings. No epithelial element was noted. She underwent surgical excision which confirmed the diagnosis of primary ovarian fibrosarcoma (the largest till date to our knowledge). Immunohistochemical analyses showed vimentin and CD 34 positivity. We speculate that ovarian fibrosarcoma at the preoperative examination might be considered in the differential diagnosis whenever a unilateral, heterogeneous, largely round solid ovarian lesion is detected.</description><identifier>ISSN: 0970-9371</identifier><identifier>EISSN: 0974-5165</identifier><identifier>DOI: 10.4103/0970-9371.103946</identifier><identifier>PMID: 23326031</identifier><language>eng</language><publisher>India: Medknow Publications and Media Pvt. Ltd</publisher><subject>Abdomen ; Care and treatment ; Case Report ; Case studies ; Diagnosis ; Excision (Surgery) ; Fibrosarcoma ; Fibrosarcoma; ovarian neoplasm; sarcoma ; Health aspects ; Tumors ; Ultrasound imaging</subject><ispartof>Journal of cytology, 2012-10, Vol.29 (4), p.255-257</ispartof><rights>COPYRIGHT 2012 Medknow Publications and Media Pvt. Ltd.</rights><rights>Copyright Medknow Publications & Media Pvt Ltd Oct 2012</rights><rights>Copyright: © Journal of Cytology 2012</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c524t-e11770ef6513698613657f4676314b949ae07dd1c1a6dd95d22142e119d3fb963</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543596/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/1247636772?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,25731,27901,27902,36989,44566,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/23326031$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ray, Sumit</creatorcontrib><creatorcontrib>Biswas, Biplab K</creatorcontrib><creatorcontrib>Mukhopadhyay, Subhalakshmi</creatorcontrib><title>Giant primary ovarian fibrosarcoma: Case report and review of pitfalls</title><title>Journal of cytology</title><addtitle>J Cytol</addtitle><description>Primary ovarian fibrosarcomas are very uncommon neoplasms; less than one hundred cases have been reported. Diagnosis can be difficult to establish and other similar appearing mesenchymal lesions must be ruled out. A 23 year old nulliparous woman presented with a huge right ovarian tumor (25 × 17 × 12 cm). Ultrasonography guided aspiration was performed and a strong possibility of fibrosarcoma was suggested based on cytomorphological findings. No epithelial element was noted. She underwent surgical excision which confirmed the diagnosis of primary ovarian fibrosarcoma (the largest till date to our knowledge). Immunohistochemical analyses showed vimentin and CD 34 positivity. We speculate that ovarian fibrosarcoma at the preoperative examination might be considered in the differential diagnosis whenever a unilateral, heterogeneous, largely round solid ovarian lesion is detected.</description><subject>Abdomen</subject><subject>Care and treatment</subject><subject>Case Report</subject><subject>Case studies</subject><subject>Diagnosis</subject><subject>Excision (Surgery)</subject><subject>Fibrosarcoma</subject><subject>Fibrosarcoma; ovarian neoplasm; sarcoma</subject><subject>Health aspects</subject><subject>Tumors</subject><subject>Ultrasound imaging</subject><issn>0970-9371</issn><issn>0974-5165</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNptUkuLFDEQDqK46-rdkzR47jHvdDwIy-A-YMGLnkM6jzHDdGdMembx31szPa47IIFUpaq-j69ShdB7ghecYPYJa4VbzRRZwEtz-QJdQoi3gkjx8ujP6Qv0ptY1xpJQzl-jC8oYlZiRS3Rzm-w4NduSBlt-N3lvCwSamPqSqy0uD_Zzs7Q1NCVsc5kaO3pw9yk8Njk22zRFu9nUt-gV2BrenewV-nHz9fvyrn34dnu_vH5onaB8agMhSuEQpSBM6k7CLVTkUklGeK-5tgEr74kjVnqvhaeUcAoo7VnstWRX6H7m9dmuzUm1yTaZYyCXlbFlSm4TjOKCWQlsHefcBdZB06RTsVdKdoEq4Poyc213_RC8C-NU7OaM9Dwzpp9mlfeGCc7EUczHE0HJv3ahTmadd2WE_g38M_QklaL_qlYWVKUxZiBzQ6rOXDNCFZedOHAt_lMFx4chuTyGmCB-BsAzwMGgagnxSTjB5rAc5jB9c5i-mZcDIB-eN_wE-LsN7A9LCrD_</recordid><startdate>20121001</startdate><enddate>20121001</enddate><creator>Ray, Sumit</creator><creator>Biswas, Biplab K</creator><creator>Mukhopadhyay, Subhalakshmi</creator><general>Medknow Publications and Media Pvt. 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subjects | Abdomen Care and treatment Case Report Case studies Diagnosis Excision (Surgery) Fibrosarcoma Fibrosarcoma ovarian neoplasm sarcoma Health aspects Tumors Ultrasound imaging |
title | Giant primary ovarian fibrosarcoma: Case report and review of pitfalls |
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