mRNA expression profiles in muscle-derived extracellular vesicles of Large White and wild boar piglets reveal their potential roles in immunity and muscle phenotype

Extracellular vesicles (EVs) known for their pivotal role in intercellular communication through RNA delivery, hold paramount implications for understanding muscle phenotypic variations in diverse pig breeds. In this study, we compared the mRNA expression profiles of muscles and muscle-derived extra...

Full description

Saved in:
Bibliographic Details
Published in:Frontiers in veterinary science 2024-10, Vol.11, p.1452704
Main Authors: Yu, Naixiang, Chang, Xiaolong, Hu, Jianchao, Li, Jianjun, Ma, Junwu, Huang, Lusheng
Format: Article
Language:English
Subjects:
exosomes
extracellular vesicles
mRNA
muscle
pig
Veterinary Science
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Extracellular vesicles (EVs) known for their pivotal role in intercellular communication through RNA delivery, hold paramount implications for understanding muscle phenotypic variations in diverse pig breeds. In this study, we compared the mRNA expression profiles of muscles and muscle-derived extracellular vesicles (M-EVs), and also examined the diversity of enriched genes in M-EVs between weaned wild boars and commercial Large White pigs with respect to their numbers and biological functions. The results of the study showed that the variation in the expression profiles of mRNAs between muscles and M-EVs was much greater than the variability between the respective breeds. Meanwhile, the enrichment trend of low-expressed genes (ranked
ISSN:2297-1769
2297-1769
DOI:10.3389/fvets.2024.1452704