Antibacterial activity and chemical composition of essential oil of Lippia microphylla Cham/Atividade antibacteriana e composicao quimica do oleo essencial de Lippia microphylla Cham

The essential oil from the fresh leaves of Lippia microphylla Cham. was obtained by hydrodistillation and characterized by gas chromatography-mass spectrometry (GC-MS). Major constituents of the oil were 1.8-cineole (18.12%), [beta]-ocimene (15.20%), bicyclogermacrene (11.63%) and caryophyllene oxid...

Full description

Saved in:
Bibliographic Details
Published in:Acta scientiarum. Biological sciences 2011-04, Vol.33 (2), p.141-144
Main Authors: Rodrigues, Fabiola Fernandes Galvao, Coutinho, Henrique Douglas Melo, Campos, Adriana Rolim, de Lima, Sidney Goncalo, da Costa, Jose Galberto Ma
Format: Article
Language:eng ; spa
Subjects:
8-cineol
8-cineole
antibacterial activity
atividade antibacteriana
Staphylococcus aureus
verbenaceae
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The essential oil from the fresh leaves of Lippia microphylla Cham. was obtained by hydrodistillation and characterized by gas chromatography-mass spectrometry (GC-MS). Major constituents of the oil were 1.8-cineole (18.12%), [beta]-ocimene (15.20%), bicyclogermacrene (11.63%) and caryophyllene oxide (8.32%). Antimicrobial activity of the oil against Gram-positive and Gram-negative bacteria was determined by gel diffusion method. The oil showed good antibacterial activity against Shigella flexneri, Escherichia coli and Streptococcus pyogenes and very good antibacterial activity against Staphylococcus aureus. Keywords: antibacterial activity, 1,8-cineole, verbenaceae, Staphylococcus aureus. Atividade antibacteriana e composicao quimica do oleo essencial de Lippia microphylla Cham. O oleo essencial das folhas frescas de Lippia microphylla Cham. foi obtido por hidrodestilacao e caracterizado por cromatografia gasosa acoplada a espectrometria de massas (CG-EM). O constituinte majoritario do oleo foi 1.8-cineol (18,12%), [beta]-ocimeno (15,20%), bicyclogermacreno (11,63%) e oxido de caryophylleno (8,32%). A atividade antimicrobiana do oleo frente as bacterias Gram-positivas e Gramnegativas foi determinada pelo metodo de difusao em gel. O oleo apresentou uma boa atividade antibacteriana frente a Shigella flexneri, Escherichia coli e Streptococcus pyogenes sendo o melhor resultado frente a Staphylococcus aureus. Palavras-chave: atividade antibacteriana, 1,8-cineol, verbenaceae, Staphylococcus aureus.
ISSN:1679-9283
1807-863X
DOI:10.4025/actascibiolsci.v33i2.5792