Secondary Leiomyosarcoma of the Lower Limb Following Uterine Smooth Muscle Tumor of Uncertain Malignant Potential

Introduction: This report presents uterine smooth muscle tumors of uncertain malignant potential course with an unpredictable clinical behavior and late metastases. Metastases have been described to the humerus, lung, and peritoneum. Case Presentation: Hereby we present the case of a 71-year-old wom...

Full description

Saved in:
Bibliographic Details
Published in:Clinical medicine insights. Case reports 2019, Vol.12, p.1179547619857680
Main Authors: García-Sánchez, Jose María, Bauza, Mónica, Pérez-García, Alberto, Mayordomo Aranda, Empar, Ruiz Valls, Alejandro
Format: Article
Language:English
Subjects:
Cancer
Case Report
Case reports
Gynecology
Medical prognosis
Metastasis
Morphology
Muscular system
NMR
Nuclear magnetic resonance
Smooth muscle
Tumors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c523t-e6e70af167e0902817f61d62397b96d4b8cc4f0e1a2599e37d0ef04a8790bd323
cites cdi_FETCH-LOGICAL-c523t-e6e70af167e0902817f61d62397b96d4b8cc4f0e1a2599e37d0ef04a8790bd323
container_end_page
container_issue
container_start_page 1179547619857680
container_title Clinical medicine insights. Case reports
container_volume 12
creator García-Sánchez, Jose María
Bauza, Mónica
Pérez-García, Alberto
Mayordomo Aranda, Empar
Ruiz Valls, Alejandro
description Introduction: This report presents uterine smooth muscle tumors of uncertain malignant potential course with an unpredictable clinical behavior and late metastases. Metastases have been described to the humerus, lung, and peritoneum. Case Presentation: Hereby we present the case of a 71-year-old woman with a past surgical history of hysterectomy and bilateral adnexectomy due to a smooth muscle tumor of unknown malignant potential, who was evaluated 6 years later after the appearance of a mass in the proximal third of the right lower limb. The mass was diagnosed as a G1 epithelioid leiomyosarcoma and was surgically removed with immediate reconstruction with a tendinous transfer to the tibialis posterior muscle to maintain foot dorsiflexion. Conclusion: Patients diagnosed with smooth uterine muscle tumors of uncertain malignant potential should be closely followed up given the possibility of recurrence and late metastases, bearing in mind uncommon locations as well, such as the lower limb.
doi_str_mv 10.1177/1179547619857680
format article
fullrecord <record><control><sourceid>proquest_doaj_</sourceid><recordid>TN_cdi_doaj_primary_oai_doaj_org_article_74ec28c7f64a4319bdfa0fe1c9b4a8ab</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1177_1179547619857680</sage_id><doaj_id>oai_doaj_org_article_74ec28c7f64a4319bdfa0fe1c9b4a8ab</doaj_id><sourcerecordid>2331596097</sourcerecordid><originalsourceid>FETCH-LOGICAL-c523t-e6e70af167e0902817f61d62397b96d4b8cc4f0e1a2599e37d0ef04a8790bd323</originalsourceid><addsrcrecordid>eNp9kk1r3DAQhk1paUKae09F0LNbfcu6FEpo2sCGFpI9C1kee7XYUiLLCfn31XbzWWh1kIbR-z4zA1NV7wn-RIhSn8ulBVeS6EYo2eBX1eEuVe9yr5_FB9XxPG9xOUwLxeTb6oARKhrG6WF1fQEuhs6mO7QCH6e7ONvk4mRR7FHeAFrFW0ho5acWncZxjLc-DGidIfkA6GKKMW_Q-TK7EdDlMsW0862Dg5StD-jcjn4INmT0K2YI2dvxXfWmt-MMx_fvUbU-_XZ58qNe_fx-dvJ1VTtBWa5BgsK2J1IB1pg2RPWSdJIyrVotO942zvEeA7FUaA1MdRh6zG2jNG47RtlRdbbndtFuzVXyUxnSROvNn0RMg7Ep-9K4URwcbVypwC1nRLddb3EPxOm2AG1bWF_2rKulnaBzZZJkxxfQlz_Bb8wQb4wUmkjBC-DjPSDF6wXmbLZxSaHMbyinrOECC_FfFWNEaIm1Kiq8V7kU5zlB_9gHwWa3GebvzSiWD8_7fzQ87EER1HvBbAd4qvpP4G8jj8FE</addsrcrecordid><sourcetype>Open Website</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2423845055</pqid></control><display><type>article</type><title>Secondary Leiomyosarcoma of the Lower Limb Following Uterine Smooth Muscle Tumor of Uncertain Malignant Potential</title><source>Publicly Available Content Database</source><source>Sage Journals GOLD Open Access 2024</source><source>PubMed Central</source><creator>García-Sánchez, Jose María ; Bauza, Mónica ; Pérez-García, Alberto ; Mayordomo Aranda, Empar ; Ruiz Valls, Alejandro</creator><creatorcontrib>García-Sánchez, Jose María ; Bauza, Mónica ; Pérez-García, Alberto ; Mayordomo Aranda, Empar ; Ruiz Valls, Alejandro</creatorcontrib><description>Introduction: This report presents uterine smooth muscle tumors of uncertain malignant potential course with an unpredictable clinical behavior and late metastases. Metastases have been described to the humerus, lung, and peritoneum. Case Presentation: Hereby we present the case of a 71-year-old woman with a past surgical history of hysterectomy and bilateral adnexectomy due to a smooth muscle tumor of unknown malignant potential, who was evaluated 6 years later after the appearance of a mass in the proximal third of the right lower limb. The mass was diagnosed as a G1 epithelioid leiomyosarcoma and was surgically removed with immediate reconstruction with a tendinous transfer to the tibialis posterior muscle to maintain foot dorsiflexion. Conclusion: Patients diagnosed with smooth uterine muscle tumors of uncertain malignant potential should be closely followed up given the possibility of recurrence and late metastases, bearing in mind uncommon locations as well, such as the lower limb.</description><identifier>ISSN: 1179-5476</identifier><identifier>EISSN: 1179-5476</identifier><identifier>DOI: 10.1177/1179547619857680</identifier><identifier>PMID: 31258342</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Cancer ; Case Report ; Case reports ; Gynecology ; Medical prognosis ; Metastasis ; Morphology ; Muscular system ; NMR ; Nuclear magnetic resonance ; Smooth muscle ; Tumors</subject><ispartof>Clinical medicine insights. Case reports, 2019, Vol.12, p.1179547619857680</ispartof><rights>The Author(s) 2019</rights><rights>2019. This work is published under http://creativecommons.org/licenses/by-nc/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>The Author(s) 2019. This work is licensed under the Creative Commons Attribution – Non-Commercial License http://creativecommons.org/licenses/by-nc/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>The Author(s) 2019 2019 SAGE Publications Ltd unless otherwise noted. Manuscript content on this site is licensed under Creative Commons Licenses</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c523t-e6e70af167e0902817f61d62397b96d4b8cc4f0e1a2599e37d0ef04a8790bd323</citedby><cites>FETCH-LOGICAL-c523t-e6e70af167e0902817f61d62397b96d4b8cc4f0e1a2599e37d0ef04a8790bd323</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591654/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2423845055?pq-origsite=primo$$EHTML$$P50$$Gproquest$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,4024,21966,25753,27853,27923,27924,27925,37012,44590,44945,45333,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31258342$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>García-Sánchez, Jose María</creatorcontrib><creatorcontrib>Bauza, Mónica</creatorcontrib><creatorcontrib>Pérez-García, Alberto</creatorcontrib><creatorcontrib>Mayordomo Aranda, Empar</creatorcontrib><creatorcontrib>Ruiz Valls, Alejandro</creatorcontrib><title>Secondary Leiomyosarcoma of the Lower Limb Following Uterine Smooth Muscle Tumor of Uncertain Malignant Potential</title><title>Clinical medicine insights. Case reports</title><addtitle>Clin Med Insights Case Rep</addtitle><description>Introduction: This report presents uterine smooth muscle tumors of uncertain malignant potential course with an unpredictable clinical behavior and late metastases. Metastases have been described to the humerus, lung, and peritoneum. Case Presentation: Hereby we present the case of a 71-year-old woman with a past surgical history of hysterectomy and bilateral adnexectomy due to a smooth muscle tumor of unknown malignant potential, who was evaluated 6 years later after the appearance of a mass in the proximal third of the right lower limb. The mass was diagnosed as a G1 epithelioid leiomyosarcoma and was surgically removed with immediate reconstruction with a tendinous transfer to the tibialis posterior muscle to maintain foot dorsiflexion. Conclusion: Patients diagnosed with smooth uterine muscle tumors of uncertain malignant potential should be closely followed up given the possibility of recurrence and late metastases, bearing in mind uncommon locations as well, such as the lower limb.</description><subject>Cancer</subject><subject>Case Report</subject><subject>Case reports</subject><subject>Gynecology</subject><subject>Medical prognosis</subject><subject>Metastasis</subject><subject>Morphology</subject><subject>Muscular system</subject><subject>NMR</subject><subject>Nuclear magnetic resonance</subject><subject>Smooth muscle</subject><subject>Tumors</subject><issn>1179-5476</issn><issn>1179-5476</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>AFRWT</sourceid><sourceid>PIMPY</sourceid><sourceid>DOA</sourceid><recordid>eNp9kk1r3DAQhk1paUKae09F0LNbfcu6FEpo2sCGFpI9C1kee7XYUiLLCfn31XbzWWh1kIbR-z4zA1NV7wn-RIhSn8ulBVeS6EYo2eBX1eEuVe9yr5_FB9XxPG9xOUwLxeTb6oARKhrG6WF1fQEuhs6mO7QCH6e7ONvk4mRR7FHeAFrFW0ho5acWncZxjLc-DGidIfkA6GKKMW_Q-TK7EdDlMsW0862Dg5StD-jcjn4INmT0K2YI2dvxXfWmt-MMx_fvUbU-_XZ58qNe_fx-dvJ1VTtBWa5BgsK2J1IB1pg2RPWSdJIyrVotO942zvEeA7FUaA1MdRh6zG2jNG47RtlRdbbndtFuzVXyUxnSROvNn0RMg7Ep-9K4URwcbVypwC1nRLddb3EPxOm2AG1bWF_2rKulnaBzZZJkxxfQlz_Bb8wQb4wUmkjBC-DjPSDF6wXmbLZxSaHMbyinrOECC_FfFWNEaIm1Kiq8V7kU5zlB_9gHwWa3GebvzSiWD8_7fzQ87EER1HvBbAd4qvpP4G8jj8FE</recordid><startdate>2019</startdate><enddate>2019</enddate><creator>García-Sánchez, Jose María</creator><creator>Bauza, Mónica</creator><creator>Pérez-García, Alberto</creator><creator>Mayordomo Aranda, Empar</creator><creator>Ruiz Valls, Alejandro</creator><general>SAGE Publications</general><general>Sage Publications Ltd</general><general>SAGE Publishing</general><scope>AFRWT</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AYAGU</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>5PM</scope><scope>DOA</scope></search><sort><creationdate>2019</creationdate><title>Secondary Leiomyosarcoma of the Lower Limb Following Uterine Smooth Muscle Tumor of Uncertain Malignant Potential</title><author>García-Sánchez, Jose María ; Bauza, Mónica ; Pérez-García, Alberto ; Mayordomo Aranda, Empar ; Ruiz Valls, Alejandro</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c523t-e6e70af167e0902817f61d62397b96d4b8cc4f0e1a2599e37d0ef04a8790bd323</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Cancer</topic><topic>Case Report</topic><topic>Case reports</topic><topic>Gynecology</topic><topic>Medical prognosis</topic><topic>Metastasis</topic><topic>Morphology</topic><topic>Muscular system</topic><topic>NMR</topic><topic>Nuclear magnetic resonance</topic><topic>Smooth muscle</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>García-Sánchez, Jose María</creatorcontrib><creatorcontrib>Bauza, Mónica</creatorcontrib><creatorcontrib>Pérez-García, Alberto</creatorcontrib><creatorcontrib>Mayordomo Aranda, Empar</creatorcontrib><creatorcontrib>Ruiz Valls, Alejandro</creatorcontrib><collection>Sage Journals GOLD Open Access 2024</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>ProQuest Central (Corporate)</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>Australia &amp; New Zealand Database</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>PubMed Central (Full Participant titles)</collection><collection>Directory of Open Access Journals</collection><jtitle>Clinical medicine insights. Case reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>García-Sánchez, Jose María</au><au>Bauza, Mónica</au><au>Pérez-García, Alberto</au><au>Mayordomo Aranda, Empar</au><au>Ruiz Valls, Alejandro</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Secondary Leiomyosarcoma of the Lower Limb Following Uterine Smooth Muscle Tumor of Uncertain Malignant Potential</atitle><jtitle>Clinical medicine insights. Case reports</jtitle><addtitle>Clin Med Insights Case Rep</addtitle><date>2019</date><risdate>2019</risdate><volume>12</volume><spage>1179547619857680</spage><pages>1179547619857680-</pages><issn>1179-5476</issn><eissn>1179-5476</eissn><abstract>Introduction: This report presents uterine smooth muscle tumors of uncertain malignant potential course with an unpredictable clinical behavior and late metastases. Metastases have been described to the humerus, lung, and peritoneum. Case Presentation: Hereby we present the case of a 71-year-old woman with a past surgical history of hysterectomy and bilateral adnexectomy due to a smooth muscle tumor of unknown malignant potential, who was evaluated 6 years later after the appearance of a mass in the proximal third of the right lower limb. The mass was diagnosed as a G1 epithelioid leiomyosarcoma and was surgically removed with immediate reconstruction with a tendinous transfer to the tibialis posterior muscle to maintain foot dorsiflexion. Conclusion: Patients diagnosed with smooth uterine muscle tumors of uncertain malignant potential should be closely followed up given the possibility of recurrence and late metastases, bearing in mind uncommon locations as well, such as the lower limb.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>31258342</pmid><doi>10.1177/1179547619857680</doi><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1179-5476
ispartof Clinical medicine insights. Case reports, 2019, Vol.12, p.1179547619857680
issn 1179-5476
1179-5476
language eng
recordid cdi_doaj_primary_oai_doaj_org_article_74ec28c7f64a4319bdfa0fe1c9b4a8ab
source Publicly Available Content Database; Sage Journals GOLD Open Access 2024; PubMed Central
subjects Cancer
Case Report
Case reports
Gynecology
Medical prognosis
Metastasis
Morphology
Muscular system
NMR
Nuclear magnetic resonance
Smooth muscle
Tumors
title Secondary Leiomyosarcoma of the Lower Limb Following Uterine Smooth Muscle Tumor of Uncertain Malignant Potential
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-23T09%3A45%3A14IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_doaj_&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Secondary%20Leiomyosarcoma%20of%20the%20Lower%20Limb%20Following%20Uterine%20Smooth%20Muscle%20Tumor%20of%20Uncertain%20Malignant%20Potential&rft.jtitle=Clinical%20medicine%20insights.%20Case%20reports&rft.au=Garc%C3%ADa-S%C3%A1nchez,%20Jose%20Mar%C3%ADa&rft.date=2019&rft.volume=12&rft.spage=1179547619857680&rft.pages=1179547619857680-&rft.issn=1179-5476&rft.eissn=1179-5476&rft_id=info:doi/10.1177/1179547619857680&rft_dat=%3Cproquest_doaj_%3E2331596097%3C/proquest_doaj_%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c523t-e6e70af167e0902817f61d62397b96d4b8cc4f0e1a2599e37d0ef04a8790bd323%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2423845055&rft_id=info:pmid/31258342&rft_sage_id=10.1177_1179547619857680&rfr_iscdi=true