The Evolution of Emerging Nanovesicle Technologies for Enhanced Delivery of Molecules into and across the Skin

This review focuses on nanovesicular carriers for enhanced delivery of molecules into and across the skin, from their design to recent emerging technologies. During the last four decades, several approaches have been used aiming to design new nanovesicles, some of them by altering the properties of...

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Bibliographic Details
Published in:Pharmaceutics 2024-02, Vol.16 (2), p.267
Main Authors: Touitou, Elka, Natsheh, Hiba
Format: Article
Language:English
Subjects:
Acne
Alcohol
dermal/transdermal drug delivery
Drug delivery systems
Enoxacin
Ethanol
ethosome
flexible
Nanoparticles
nanovesciles
Permeability
Phospholipids
Review
Skin
Skin diseases
soft
Surfactants
Transdermal medication
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Summary:This review focuses on nanovesicular carriers for enhanced delivery of molecules into and across the skin, from their design to recent emerging technologies. During the last four decades, several approaches have been used aiming to design new nanovesicles, some of them by altering the properties of the classic phospholipid vesicle, the liposome. Phospholipid nanovesicular systems, including the phospholipid soft vesicles as well as the non-phospholipid vesicular carries, are reviewed. The altered nanovesicles have served in the manufacture of various cosmetic products and have been investigated and used for the treatment of a wide variety of skin conditions. The evolution and recent advances of these nanovesicular technologies are highlighted in this review.
ISSN:1999-4923
1999-4923
DOI:10.3390/pharmaceutics16020267