Clinical implications of peripheral eosinophil count at diagnosis in patients newly diagnosed with microscopic polyangiitis and granulomatosis with polyangiitis

• Published in: Arthritis research & therapy 2023-12, Vol.25 (1), p.245-245, Article 245
• Main Authors: Ha, Jang Woo, Ahn, Sung Soo, Song, Jason Jungsik, Park, Yong-Beom, Lee, Sang-Won
• Format: Article
• Language: English
• Subjects: Activity; Acute coronary syndromes; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis - diagnosis; Antibodies, Antineutrophil Cytoplasmic; Arthritis; Blood cell count; Classification; Correlation analysis; Cross-Sectional Studies; Diagnosis; Drugs; Eosinophil; Eosinophils; Female; Granulomatosis with polyangiitis; Granulomatosis with Polyangiitis - diagnosis; Health aspects; Hospitals; Humans; Immunosuppressive agents; Inflammatory diseases; Male; Measurement; Medical diagnosis; Microscopic polyangiitis; Microscopic Polyangiitis - diagnosis; Middle Aged; Mortality; Pathogenesis; Patients; Prognosis; Retrospective Studies; Rheumatology; Signal transduction; Survival analysis; Vein & artery diseases; Wegener's granulomatosis
• ISSN: 1478-6362; 1478-6354; 1478-6362
• DOI: 10.1186/s13075-023-03233-1

This study investigated the clinical implications of peripheral eosinophil count at diagnosis in estimating cross-sectional antineutrophil cytoplasmic antibody-associated vasculitis (AAV) activity and predicting all-cause mortality during follow-up in patients newly diagnosed with microscopic polyangiitis (MPA) and granulomatosis with polyangiitis (GPA). This study included 224 immunosuppressive drug-naïve patients with peripheral eosinophil count at diagnosis