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Different care mode alter composition and function of gut microbiota in cerebral palsy children

Specialized care is essential for the recovery of children with cerebral palsy (CP). This study investigates how different care modes impact the gut microbiota. Fecal samples from 32 children were collected, among whom those cared for by family ( = 21) were selected as the observation group, and tho...

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Bibliographic Details
Published in:Frontiers in pediatrics 2024-08, Vol.12, p.1440190
Main Authors: Lyu, Jinli, Zhang, Xiaowei, Xiong, Shenghua, Wu, Hui, Han, Jing, Xie, Yongjie, Qiu, Feifeng, Yang, Zhenyu, Huang, Congfu
Format: Article
Language:English
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Summary:Specialized care is essential for the recovery of children with cerebral palsy (CP). This study investigates how different care modes impact the gut microbiota. Fecal samples from 32 children were collected, among whom those cared for by family ( = 21) were selected as the observation group, and those cared for by children's welfare institutions ( = 11) were selected as the control group (registration number of LGFYYXLL-024). The gut microbiota profiles were analyzed. There was no significant difference in the α-diversity of the gut microbiota and the abundance at the phylum level. However, at the genus level, the observation group showed a significant increase in the abundance of butyrate-producing bacteria and (  
ISSN:2296-2360
2296-2360
DOI:10.3389/fped.2024.1440190