Examining Quality of Life After Treatment with Azelaic and Pyruvic Acid Peels in Women with Acne Vulgaris

This randomized parallel study aims to investigate the azelaic acid (AA), and pyruvic acid (PA) peels treatment effect on health-related quality of life (QOL) in young adult women with acne vulgaris. The participants were 120 female undergraduate students, with mild to moderate facial acne and an av...

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Bibliographic Details
Published in:Clinical, cosmetic and investigational dermatology cosmetic and investigational dermatology, 2020-01, Vol.13, p.469-477
Main Authors: Chilicka, Karolina, Rogowska, Aleksandra M, Szyguła, Renata, Taradaj, Jakub
Format: Article
Language:English
Subjects:
acid peels
Acids
Acne
Antiacne agents
azelaic acid
Care and treatment
Cosmetics
Cosmetology
Cotton
Dermatology
dlqi
Erythema
Health aspects
Likert scale
Original Research
Patients
pyruvic acid
Quality of life
Self esteem
Skin
skindex-29
Variance analysis
women
Women college students
Womens health
Young adults
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Summary:This randomized parallel study aims to investigate the azelaic acid (AA), and pyruvic acid (PA) peels treatment effect on health-related quality of life (QOL) in young adult women with acne vulgaris. The participants were 120 female undergraduate students, with mild to moderate facial acne and an average age of 22 years old (M = 22.2, SD = 16.1). Eligibility criteria were as follows: female gender, 18-25 years of age, no dermatological treatment within the last 12 months and mild to moderate papulopustular acne. Patients were randomly divided into two groups, the first group was treated with AA, and the second group was treated with PA. Both groups received treatment every 2 weeks, for a total of 12 weeks. The Hellgren-Vincent scale was used to assess acne severity, and the Dermatology Life Quality Index (DLQI) and Skindex-29 were used to evaluate the quality of life of each patient. These scores were calculated before treatment, and after finishing the final treatment. All scoring systems used (Hellgren-Vincent scale, DLQI, and Skindex-29) demonstrated improvement in both groups. QOL scores were slightly better in the group using pyruvic acid compared with azelaic acid. Both AA and PA have a significant impact on the objective assessment of acne symptoms, as well as the subjectively measured quality of life of young adult women with acne. There is a slightly greater improvement in QOL scores with PA compared with AA peeling treatment.
ISSN:1178-7015
1178-7015
DOI:10.2147/CCID.S262691