Acute inflammatory response following lower-and upper-body Wingate anaerobic test in elite gymnasts in relation to iron status

• Published in: Frontiers in physiology 2024-07, Vol.15, p.1383141
• Main Authors: Kochanowicz, Andrzej, Waldziński, Tomasz, Niespodziński, Bartłomiej, Brzezińska, Paulina, Kochanowicz, Magdalena, Antosiewicz, Jedrzej, Mieszkowski, Jan
• Format: Article
• Language: English
• Subjects: anaerobic exercises; inflammation; iron status; male athletes; muscle damage; oxidative stress; Physiology
• ISSN: 1664-042X; 1664-042X
• DOI: 10.3389/fphys.2024.1383141

Artistic gymnastics is one of the most demanding sports disciplines, with the athletes demonstrating extremely high levels of explosive power and strength. Currently, knowledge of the effect of gymnastic training adaptation on exercise-induced inflammatory response is limited. The study aimed to evaluate inflammatory response following lower- and upper-body high-intensity exercise in relation to the iron status in gymnasts and non-athletes. Fourteen elite male artistic gymnasts (EAG, 20.6 ± 3.3 years old) and 14 physically active men (PAM, 19.9 ± 1.0 years old) participated in the study. Venous blood samples were taken before and 5 min and 60 min after two variants of Wingate anaerobic test (WAnT), upper-body and lower-body WAnT. Basal iron metabolism (serum iron and ferritin) and acute responses of selected inflammatory response markers [interleukin (IL) 6, IL-10, and tumour necrosis factor α] were analysed. EAG performed significantly better during upper-body WAnT than PAM regarding relative mean and peak power. The increase in IL-6 levels after upper-body WAnT was higher in EAG than in PAM; the opposite was observed after lower-body WAnT. IL-10 levels were higher in EAG than in PAM, and tumour necrosis factor α levels were higher in PAM than those in EAG only after lower-body WAnT. The changes in IL-10 correlated with baseline serum iron and ferritin in PAM. Overall, gymnastic training is associated with the attenuation of iron-dependent post-exercise anti-inflammatory cytokine secretion.