Correlation between Clinical and Wastewater SARS-CoV-2 Genomic Surveillance, Oregon, USA

SARS-CoV-2 variant proportions in a population can be estimated through genomic sequencing of clinical specimens or wastewater samples. We demonstrate strong pairwise correlation between statewide variant estimates in Oregon, USA, derived from both methods (correlation coefficient 0.97). Our results...

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Bibliographic Details
Published in:Emerging infectious diseases 2022-09, Vol.28 (9), p.1906-1908
Main Authors: Kaya, Devrim, Falender, Rebecca, Radniecki, Tyler, Geniza, Matthew, Cieslak, Paul, Kelly, Christine, Lininger, Noah, Sutton, Melissa
Format: Article
Language:English
Subjects:
coronavirus disease
Coronaviruses
Correlation analysis
Correlation between Clinical and Wastewater SARS-CoV-2 Genomic Surveillance, Oregon, USA
COVID-19
Disease control
DNA sequencing
Estimates
Expedited
Health aspects
Health surveillance
Methods
Nucleotide sequencing
Regression analysis
Research Letter
respiratory infections
SARS
SARS-CoV-2
Sentinel health events
Severe acute respiratory syndrome coronavirus 2
Wastewater
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Summary:SARS-CoV-2 variant proportions in a population can be estimated through genomic sequencing of clinical specimens or wastewater samples. We demonstrate strong pairwise correlation between statewide variant estimates in Oregon, USA, derived from both methods (correlation coefficient 0.97). Our results provide crucial evidence of the effectiveness of community-level genomic surveillance.
ISSN:1080-6040
1080-6059
DOI:10.3201/eid2809.220938